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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Streptozocin

Zanosar 1 gm powder vial



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Streptozocin volume of distribution

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What is Streptozocin

An antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals.

Streptozocin mechanism of action

Although its mechanism of action is not completely clear, streptozocin is known to inhibit DNA synthesis, interfere with biochemical reactions of NAD and NADH, and inhibit some enzymes involved in gluconeogenesis. Its activity appears to occur as a result of formation of methylcarbonium ions, which alkylate or bind with many intracellular molecular structures including nucleic acids. Its cytotoxic action is probably due to cross-linking of strands of DNA, resulting in inhibition of DNA synthesis.

Dosage forms of Streptozocin

Form Route Strength
Powder, for solution intravenous 100 mg/mL
Powder for solution intravenous 1 g
Prescription Generics


International Brands



2-Deoxy-2-(((methylnitrosoamino)carbonyl)amino)-D-glucopyranose 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose


Teva Parenteral Medicines, Inc.

CAS number






Affected organisms

Humans and other mammals

Indication of Streptozocin

For the treatment of malignant neoplasms of pancreas (metastatic islet cell carcinoma).

Toxicity of Streptozocin

Symptoms of overdose include nausea and vomiting, anorexia, myelosuppression; and nephrotoxicity.

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