Save up -80% on Succimer
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
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2019 Price of Chemet
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We offer free Chemet coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Succimer every time. What are you waiting for? Claim your prescription drug card now!
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Succimer volume of distribution
In a study performed in healthy adult volunteers, after a single dose of (14)Csuccimer at 16, 32, or 48 mg/kg, absorption was rapid but variable with peak blood radioactivity levels between one and two hours. On average, 49% of the radiolabeled dose was excreted: 39% in the feces, 9% in the urine and 1% as carbon dioxide from the lungs. Since fecal excretion probably represented nonabsorbed drug, most of the absorbed drug was excreted by the kidneys. The apparent elimination half-life of the radiolabeled material in the blood was about two days.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Succimer
A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.
Succimer mechanism of action
Succimer is a heavy metal chelator. It binds with high specificity to ions of lead in the blood to form a water-soluble complex that is subsequently excreted by the kidneys. Succimer can also chelate mercury, cadmium, and arsenic in this manner.
Dosage forms of Succimer
Dimercaptosuccinic acid DMSA
RECORDATI RARE DISEASES, INC.
Humans and other mammals
Indication of Succimer
For the treatment of lead poisoning in pediatric patients with blood lead levels above 45 micro;g/dL. May also be used to treat mercury or arsenic poisoning.
Toxicity of Succimer
Oral LD sub50 /sub in mice is over 5011 mg/kg. Doses of 2300 mg/kg in the rat and 2400 mg/kg in the mouse produced ataxia, convulsions, labored respiration and frequently death. No case of overdosage has been reported in humans. Limited data indicate that succimer is dialyzable.
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