Save up -80% on Succimer
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2018 Price of Succimer
Chemet 100 mg capsule
* price without discount in nearest pharmacy. Price may vary.
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Succimer volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Succimer
A mercaptodicarboxylic acid used as an antidote to heavy metal poisoning because it forms strong chelates with them.
Succimer mechanism of action
Succimer is a heavy metal chelator. It binds with high specificity to ions of lead in the blood to form a water-soluble complex that is subsequently excreted by the kidneys. Succimer can also chelate mercury, cadmium, and arsenic in this manner.
Dosage forms of Succimer
Dimercaptosuccinic acid DMSA
RECORDATI RARE DISEASES, INC.
Humans and other mammals
Indication of Succimer
For the treatment of lead poisoning in pediatric patients with blood lead levels above 45 micro;g/dL. May also be used to treat mercury or arsenic poisoning.
Toxicity of Succimer
Oral LD sub50 /sub in mice is over 5011 mg/kg. Doses of 2300 mg/kg in the rat and 2400 mg/kg in the mouse produced ataxia, convulsions, labored respiration and frequently death. No case of overdosage has been reported in humans. Limited data indicate that succimer is dialyzable.
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