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Price of Sulfadiazine
Sulfadiazine 500 mg tablet
* price without discount in nearest pharmacy. Price may vary.
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Sulfadiazine volume of distribution
What is Sulfadiazine
One of the short-acting sulfonamides used in combination with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome and in newborns with congenital infections. (PubChem)
Sulfadiazine mechanism of action
Sulfadiazine is a competitive inhibitor of the bacterial enzyme dihydropteroate synthetase. This enzyme is needed for the proper processing of para-aminobenzoic acid (PABA) which is essential for folic acid synthesis. The inhibited reaction is necessary in these organisms for the synthesis of folic acid.
Dosage forms of Sulfadiazine
Coptin Oral Suspension
Axcan Pharma Inc
Enteric bacteria and other eubacteria
Indication of Sulfadiazine
For the treatment of rheumatic fever and meningococcal meningitis
Toxicity of Sulfadiazine
Oral LD sub 50 /sub in mouse is 1500 mg/kg.
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