Save up -80% on Sulfamethazine
Note: this is a drug discount program, not an insurance plan.
2018 Price of Sulfamethazine
* price without discount in nearest pharmacy. Price may vary.
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Sulfamethazine volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
Sulfamethazine mechanism of action
Sulfonamides inhibit the enzymatic conversion of pteridine and p-aminobenzoic acid (PABA) to dihydropteroic acid by competing with PABA for binding to dihydrofolate synthetase, an intermediate of tetrahydrofolic acid (THF) synthesis. THF is required for the synthesis of purines and dTMP and inhibition of its synthesis inhibits bacterial growth. Pyrimethamine and trimethoprim inhibit dihydrofolate reductase, another step in THF synthesis, and therefore act synergistically with the sulfonamides.
Dosage forms of Sulfamethazine
Shepherd Pharmaceuticals Inc.
Toxicity of Sulfamethazine
Sulfamethazine may cause nausea, vomiting, diarrhea and hypersensitivity reactions. Hematologic effects such as anemia, agranulocytosis, thrombocytopenia and hemolytic anemia in patients with glucose-6-phosphate dehydrogenase deficiency may also occur. Sulfamethoxazole may displace bilirubin from albumin binding sites causing jaundice or kernicterus in newborns.
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