Save up -80% on Sulfamethoxazole
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Bactrim
|$6.28||20 tablets/160 mg|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Sulfamethoxazole coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Sulfamethoxazole every time. What are you waiting for? Claim your prescription drug card now!
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Sulfamethoxazole volume of distribution
The volume of distribution is approximately 1.6 L/kg for trimethoprim and approximately 0.26 L/kg for sulfamethoxazole, while the plasma protein binding reaches 37% Page 3 Bactrim ® PI 160927 3 for trimethoprim and 53% for sulfamethoxazole.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Sulfamethoxazole
A bacteriostatic antibacterial agent that interferes with folic acid synthesis in susceptible bacteria. Its broad spectrum of activity has been limited by the development of resistance. (From Martindale, The Extra Pharmacopoeia, 30th ed, p208)
Sulfamethoxazole mechanism of action
Sulfonamides inhibit the enzymatic conversion of pteridine and p-aminobenzoic acid (PABA) to dihydropteroic acid by competing with PABA for binding to dihydrofolate synthetase, an intermediate of tetrahydrofolic acid (THF) synthesis. THF is required for the synthesis of purines and dTMP and inhibition of its synthesis inhibits bacterial growth. Pyrimethamine and trimethoprim inhibit dihydrofolate reductase, another step in THF synthesis, and therefore act synergistically with the sulfonamides.
Dosage forms of Sulfamethoxazole
Apo Sulfamethoxazole Tab 500mg
Gram negative and gram positive bacteria
Indication of Sulfamethoxazole
For the treatment bacterial infections causing bronchitis, prostatitis and urinary tract infections.
Toxicity of Sulfamethoxazole
Sulfamethoxazole may cause nausea, vomiting, diarrhea and hypersensitivity reactions. Hematologic effects such as anemia, agranulocytosis, thrombocytopenia and hemolytic anemia in patients with glucose-6-phosphate dehydrogenase deficiency may also occur. Sulfamethoxazole may displace bilirubin from albumin binding sites causing jaundice or kernicterus in newborns.
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