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Price of Sulfanilamide
AVC Vaginal 15% Cream 120 gm Tube
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Sulfanilamide volume of distribution
What is Sulfanilamide
Sulfanilamide is a molecule containing the sulfonamide functional group attached to an aniline. (Wikipedia)
Sulfanilamide mechanism of action
Sulfanilamide is a competitive inhibitor of bacterial enzyme dihydropteroate synthetase. This enzyme normally uses para-aminobenzoic acid (PABA) for synthesizing the necessary folic acid. The inhibited reaction is normally necessary in these organisms for the synthesis of folic acid. Without it, bacteria cannot replicate.
Dosage forms of Sulfanilamide
4-Aminobenzene sulfonic acid amide
Candida albicans and other yeasts
Indication of Sulfanilamide
For the treatment of vulvovaginitis caused by i Candida albicans /i .
Toxicity of Sulfanilamide
Oral, mouse LD sub 50 /sub = 3700 mg/kg; Intravenous, mouse LD sub 50 /sub = 621 mg/kg; Oral, rabbit LD sub 50 /sub = 1300 mg/kg. Side effects include itching, burning, skin rash, redness, swelling, or other sign of irritation not present before use of this medicine and long-term use of sulfonamides may cause cancer of the thyroid gland.
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