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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Sulfisoxazole

Sulfisoxazole crystals

$1.01

g

* price without discount in nearest pharmacy. Price may vary.

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Sulfisoxazole volume of distribution

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What is Sulfisoxazole

A short-acting sulfonamide antibacterial with activity against a wide range of gram- negative and gram-positive organisms.

Sulfisoxazole mechanism of action

Sulfisoxazole is a competitive inhibitor of the enzyme dihydropteroate synthetase. It inhibits bacterial synthesis of dihydrofolic acid by preventing the condensation of the pteridine with para-aminobenzoic acid (PABA), a substrate of the enzyme dihydropteroate synthetase. The inhibited reaction is necessary in these organisms for the synthesis of folic acid.

Dosage forms of Sulfisoxazole

FormRouteStrength
Tabletoral500 mg
Granule, for suspensionoral
Powder for suspensionoral
Prescription Generics

true

International Brands

Apo Sulfisoxazole Tab 500mg

Synonyms

3,4-Dimethyl-5-sulfanilamidoisoxazole 3,4-Dimethyl-5-sulfonamidoisoxazole

Manufacturers

Apotex Inc

CAS number

127-69-5

UNII

740T4C525W

State

solid

Affected organisms

Enteric bacteria and other eubacteria

Indication of Sulfisoxazole

For the treatment of severe, repeated, or long-lasting urinary tract infections, meningococcal meningitis, acute otitis media, trachoma, inclusion conjunctivitis, nocardiosis, chancroid, toxoplasmosis, malaria and other bacterial infections.

Toxicity of Sulfisoxazole

LD sub 50 /sub =6800 mg/kg (Orally in mice)

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