Save up -80% on Tadalafil
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Cialis
|$114.26||30 tablets/5 mg|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Cialis coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Tadalafil every time. What are you waiting for? Claim your prescription drug card now!
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Tadalafil volume of distribution
|Adcirca||Tablet||20 mg/1||Oral||Avera Mc Kennan Hospital|
|Adcirca||Tablet||20 mg/1||Oral||United Therapeutics|
|Adcirca||Tablet||20 mg/1||Oral||Aphena Pharma Solutions Tennessee, Inc.|
|Cialis||Tablet, film coated||5 mg/1||Oral||Cardinal Health|
|Cialis||Tablet, film coated||10 mg/1||Oral||Eli Lilly & Co. Ltd.|
|Cialis||Tablet, film coated||20 mg/1||Oral||Rebel Distributors|
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Tadalafil
Tadalafil is an orally adminstered drug used to treat male erectile dysfunction (impotence). It is marketed worldwide under the brand name Cialis. It is a phosphodiesterase 5 (PDE5) inhibitor. Tadalafil’s distinguishing pharmacologic feature is its longer half-life (17.5 hours) compared with Viagra and Levitra (4-5 hours). This longer half-life results in a longer duration of action and is, in part, responsible for the Cialis nickname of the “weekend pill.” This longer half-life also is the basis of current investigation for tadalafil’s use in pulmonary arterial hypertension as a once-daily therapy. (Wikipedia)
Tadalafil mechanism of action
Tadalafil inhibits the cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum located around the penis. Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle. This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase type 5 (PDE5) by tadalafil enhances erectile function by increasing the amount of cGMP.
Dosage forms of Tadalafil
Apo-tadalafil, Dom-tadalafil, Ipg-tadalafil, Jamp-tadalafil, Mar-tadalafil, Mint-tadalafil, Mylan-tadalafil, PMS-tadalafil, Priva-tadalafil, Ran-tadalafil, Riva-tadalafil, Tadalafil Mylan, Teva-tadalafil
Act Tadalafil, Adcirca, Cialis, Tadalafil, Tadalafil Mylan, Teva-tadalafil
Actavis Pharma Company, Aphena Pharma Solutions Tennessee, Avera Mc Kennan Hospital, Bryant ranch prepack, Cardinal Health, Dispensing Solutions, Eli Lilly & Co., Eli Lilly Nederland B.V., Pd Rx Pharmaceuticals, Physicians Total Care, Pro Doc Limitee, Rebel Distributors, Sanis Health Inc, International Pharmaceutical Generics, Teva
Humans and other mammals
Indication of Tadalafil
Used for the treatment of erectile dysfunction.
Toxicity of Tadalafil
Oral, Rat LDsub50/sub = 2000 mg/kg, no deaths or toxicity.
RX24 Drugs Disclaimer: consult your healthcare provider before buying a Tadalafil on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.
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What is a Cialis?
Cialis tablets are drugs that have similarities with the original in terms of pharmaceutical, biological and therapeutic properties. The active ingredient of Cialis is tadalafil. This substance, improving erection, gives a man the ability to successfully perform sexual intercourse. The drug is valid for 36 hours and it is considered the best indicator among all tablets for potency.
If in the morning you took Cialis pill, then even the next day you can please your partner with a stable and high-quality erection. The effect of taking the pill is already apparent after 16 minutes, but, like any other pills of this kind, the medicine acts in the presence of sexual arousal, which means that it should be taken at least 16 minutes before the alleged sex.
Cialis tablets are also available in the “Soft” version. Difference Cialis Soft from other tablets of this type – in the speed of onset of effect (Soft tablets work faster than usual). In addition, these tablets dissolve under the tongue and can be combined with alcohol and fatty foods.
The minimum single dose of Cialis use is 10 mg (1/2 tablet). The maximum daily dose is 20 mg (1 tablet). It is not recommended to take Cialis more often 1 time per day, since the duration of action of this drug is up to 36 hours.