Save up -80% on Tapentadol

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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Tapentadol


* price without discount in nearest pharmacy. Price may vary.

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Tapentadol volume of distribution

Following IV administration, volume of distribution is 540 98 L.

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What is Tapentadol

Opioid analgesic for treatment of moderate to severe pain. FDA approved on Nov 20, 2008.

Tapentadol mechanism of action

Tapendadol causes large increases in levels of extracellular norepinephrine (NE) due to a dual mechanism of action involving mu opioid receptor (MOR) agonism as well as noradrenaline reuptake inhibition.

Dosage forms of Tapentadol

Solutionoral20 mg/mL
Tabletoral50 mg/1
Tablet, film coatedoral100 mg/1
Prescription Generics


International Brands



BN-200 CG-5503


Stat Rx USA

CAS number






Affected organisms

Humans and other mammals

Indication of Tapentadol

The immediate-release formulation of tapentadol is indicated for the relief of moderate to severe acute pain. The long-acting formulation serves as a continuous, around-the-clock analgesic that is indicated for the relief of moderate to severe chronic pain or neuropathic pain associated with diabetic peripheral neuropathy.

Toxicity of Tapentadol

Oral, rabbit: LD50 = 3200 mg/kg; Oral, mouse: LD50 = 300 mg/kg; Oral, rat: LD50: 980 mg/kg; The most common reasons for discontinuation due to adverse events were dizziness, nausea, vomiting, somnolence, and headache.

RX24 Drugs Disclaimer: before buying a Tapentadol on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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