Save up -80% on Tapentadol
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Nucynta
|$397.28||60 tablets/50 mg|
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Nucynta coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Tapentadol every time. What are you waiting for? Claim your prescription drug card now!
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Tapentadol volume of distribution
Bioavailability, immediate release (IR), 86 mg: 32%; Bioavailability, extended release (ER), 86 mg: 32%; Cmax, IR: 64.2 ng/mL; Cmax, ER: 22.5 ng/mL; T max, IR: 1.5 hours; T max, ER: 5.0 hours; Tapentadol accumulates following multiple repeat doses. Following IV administration, volume of distribution is 540 ± 98 L.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Tapentadol
Opioid analgesic for treatment of moderate to severe pain. FDA approved on Nov 20, 2008.
Tapentadol mechanism of action
Tapendadol causes large increases in levels of extracellular norepinephrine (NE) due to a dual mechanism of action involving mu opioid receptor (MOR) agonism as well as noradrenaline reuptake inhibition.
Dosage forms of Tapentadol
|Tablet, film coated||oral||100 mg/1|
Stat Rx USA
Humans and other mammals
Indication of Tapentadol
The immediate-release formulation of tapentadol is indicated for the relief of moderate to severe acute pain. The long-acting formulation serves as a continuous, around-the-clock analgesic that is indicated for the relief of moderate to severe chronic pain or neuropathic pain associated with diabetic peripheral neuropathy.
Toxicity of Tapentadol
Oral, rabbit: LD50 = 3200 mg/kg; Oral, mouse: LD50 = 300 mg/kg; Oral, rat: LD50: 980 mg/kg; The most common reasons for discontinuation due to adverse events were dizziness, nausea, vomiting, somnolence, and headache.
RX24 Drugs Disclaimer: consult your healthcare provider before buying a Tapentadol on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.
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What is a Nucynta?
Nucynta is an opioid analgesic drug. An opioid is sometimes called a drug. Nukint is used to treat moderate to severe pain. An extended release form of tapentadol (Nucynta ER) for round-the-clock treatment of pain that is not controlled by other medications. It is not used as needed for pain. You should not use Nucynta if you have severe breathing problems or a bowel obstruction called paralytic ileus.
Do not use Nucynta if you have used a MAO inhibitor in the last 14 days. Dangerous drug interactions can occur. MAO inhibitors include isocarboxazid, linezolid, methylene blue injection, fenelzine, rasagiline, selegiline, or tranylcypromine.
Nucynta may slow down or stop your breathing, especially when you start using this medicine or when your dose changes. Never take this medicine in large quantities or for longer than prescribed. Do not crush, break or open an extended release tablet. Swallow it whole to avoid exposure to a potentially lethal dose.