Save up -80% on Tasimelteon
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Hetlioz
|$14,445||30 capsules (20mg)|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Tasimelteon coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Tasimelteon every time. What are you waiting for? Claim your prescription drug card now!
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Tasimelteon volume of distribution
The apparent oral volume of distribution of tasimelteon at steady state in young healthy subjects is approximately 56 – 126 L.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Tasimelteon
Tasimelteon is a selective dual melatonin receptor agonist indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (N24HSWD). Occurring commonly in blind individuals without light perception, this condition is often characterized by periods of night-time insomnia and day-time sleepiness. In blind individuals, a lack of light stimulation causes an extension of the 24-hour circadian cycle and can lead to progressively delayed sleep onset. By activating melatonin receptors MT1 and MT2 in the suprachiasmatic nucleus of the brain, tasimelteon has been shown to improve sleep by resynchronizing the circadian rhythm through its “non-photic” mechanism. Tasimelteon is currently the only drug available for the treatment of N24HSWD and was granted orphan drug status by the FDA in 2010.
Tasimelteon mechanism of action
Tasimelteon is a selective dual agonist of the melatonin receptors MT1 and MT2.
Dosage forms of Tasimelteon
Vanda Pharmaceuticals Inc.
Indication of Tasimelteon
Tasimelteon is indicated for the treatment of Non-24-Hour Sleep-Wake Disorder (N24HSWD).
Toxicity of Tasimelteon
The most common adverse reactions are headache, increased alanine aminotransferase, nightmares or unusual dreams, and upper respiratory or urinary tract infections. There are currently no adequate or well-controlled studies that suggest that tasimelteon is safe to use during pregnancy. In animal studies, administration of tasimelteon during pregnancy resulted in developmental toxicity (embryofetal mortality, neurobehavioral impairment, and decreased growth and development in offspring) at doses greater than those used clinically. During clinical trials, rats did not self-administer tasimelteon, suggesting that the drug does not have a potential for abuse.
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