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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Kerydin

$606.701 bottle (4ml) 5% topical solution
Price with discount in nearest pharmacy. Price may vary.

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Tavaborole volume of distribution

The pharmacokinetics of tavaborole was investigated in 24 subjects with distal subungual onychomycosis involving at least 4 toenails (including at least 1 great toenail) following a single dose and a 2-week daily topical application of 200 uL of a 5% solution of tavaborole to all ten toenails and 2 mm of skin surrounding each toenail.

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2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Tavaborole

Tavaborale is a novel, boron-based topical antifungal medication for the treatment of onychomycosis, a fungal infection of the nail and nail bed due to iTrichophyton rubrum/i or iTrichophyton mentagrophytes/i infection. Tavaborole functions by inhibiting Leucyl-tRNA synthetase, or LeuRS, an essential fungal enzyme required for protein synthesis and for the catalysis of ATP-dependent ligation of L-leucine to tRNA(Leu).

Tavaborole mechanism of action

Tavaborole exerts its antifungal activity by blocking cellular protein synthesis through the formation of an adduct with cytoplasmic leucyl-aminoacyl transfer RNA (tRNA) synthetase.

Dosage forms of Tavaborole

DrugDosageQuantityPrice
Kerydin5%4ml$625
Kerydin5%10ml$1,508

Prescription Generics

false

International Brands

Kerydin

Synonyms

5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole 5-Fluoro-2,1-benzoxaborol-1(3H)-ol

Manufacturers

Anacor Pharmaceuticals, Inc

CAS number

174671-46-6

UNII

K124A4EUQ3

State

solid

Affected organisms

Yeast and other Trichophyton or Microsporum fungi

Indication of Tavaborole

Indicated for the treatment of onychomycosis (a fungal infection) of the toenails due to iTrichophyton rubrum/i or iTrichophyton mentagrophytes/i.

Toxicity of Tavaborole

Tavaborole is generally well tolerated with most adverse events reported as mild and not related to treatment. Treatment related adverse events that occurred in 1 % of participants include application site exfoliation, application site erythema, and application site dermatitis, and ingrown toenail.

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