Save up -80% on Tazarotene
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Tazorac
|$118.55||1 tube (30g) 0.1% cream|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Tazarotene coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Tazarotene every time. What are you waiting for? Claim your prescription drug card now!
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Tazarotene volume of distribution
Dosing normal skin topically under occlusion, 5% of the dose was recovered in the stratum corneum and 0.5% was recovered in the epidermis-dermis layers. In psoriatic patients, 1.4% of the topical doses applied without occlusion was recovered in the stratum corneum and 2.4% was recovered in the epidermis-dermis layers.
Tazarotene and “tazarotenic acid” are extensively bound (more than 99%) to human plasma and albumin. The blood to plasma ration of 14C-tazarotene was less than one, indicating a greater affinity toward plasma proteins than red blood cells.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Tazarotene
Tazarotene (marketed as Tazorac, Avage and Zorac) is a prescription topical retinoid sold as a cream or gel. This medication is approved for treatment of psoriasis, acne, and sun damaged skin (photodamage). (Wikipedia)
Tazarotene mechanism of action
Although the exact mechanism of tazarotene action is not known, studies have shown that the active form of the drug (tazarotenic acid) binds to all three members of the retinoic acid receptor (RAR) family: RARa, RARb, and RARg, but shows relative selectivity for RARb, and RARg and may modify gene expression. It also has affinity for RXR receptors.
Dosage forms of Tazarotene
|Tazorac Cream||0.05%||30g Cream||$69.00|
|Tazorac Cream||0.10%||60g Cream||$130.00|
|Tazorac Cream||0.10%||90g Cream||$189.80|
|Tazorac Cream||0.10%||90g Cream||$189.80|
Humans and other mammals
Indication of Tazarotene
Used to treat psoriasis, acne and sun damaged skin (photodamage).
Tazorac is prescribed by your doctor in the following cases:
- damage to the skin by thermal effects;
- psoriasis, scars, acne, sunburn;
- acne eruption.
Important to know: in the case of hypersensitivity to the constituents of the drug should immediately seek medical attention.
Toxicity of Tazarotene
Excessive topical use may lead to marked redness, peeling, or discomfort. Oral ingestion of the drug may affect liver function causing hypertriglyceridemia. Other symptoms may include conjunctival irritation, hair loss, headache, edema, fatigue, dermatitis, nausea, and visual disturbances. Oral administration of this material to rats and rabbits at doses of 0.20 mg/kg/day (rabbits) and 0.25 mg/kg/day (rats) resulted in developmental toxicity. A no effect level of 0.05 mg/kg/day was established. Similar teratogenic effects have been reported for other retinoid compounds.
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What is Tazorac?
Tazorac is a highly effective retinoid in the third generation for the treatment of skin pathologies. The effectiveness of the drug is in line with hormonal corticosteroid drugs. It has a minimal toxicity, and the effect of treatment is observed after a weekly application.
The active substance of the drug is tazarotene – 0,05%, auxiliary – benzyl alcohol. Produced in the form of a cream, ointment or gel. Packed in tubs of 15 grams and selling as prescribed drug with coupons. The effect of Tazorac is due to the properties of tazarotene in the drug.
Under the influence of the drug, the epithelium regenerates, the metabolism of the cells of the epidermis is normalized, the anti-inflammatory effect appears, the skin’s fat content decreases, the texture and the external state of the skin improve.