Save up -80% on Telbivudine
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Tyzeka
|price without discount in nearest pharmacy. Price may vary.|
We offer free Telbivudine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Telbivudine every time. What are you waiting for? Claim your prescription drug card now!
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Telbivudine volume of distribution
8.2 ± 4.1 l/kg
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Telbivudine
Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.
Telbivudine mechanism of action
Telbivudine 5’triphosphate inhibits HBV DNA polymerase (reverse transcriptase) by competing with the natural substrate, thymidine 5’triphosphate. This leads to the chain termination of DNA synthesis, thereby inhibiting viral replication. Incorporation of telbivudine 5’triphosphate into viral DNA also causes DNA chain termination, resulting in inhibition of HBV replication. Telbivudine inhibits anticompliment or second-strand DNA.
Dosage forms of Telbivudine
|Film-coated tablet||Oral use||600 mg|
|Oral solution||Oral use||20 mg/ml|
Novartis Pharmaceuticals Canada Inc
Hepatitis B virus
Indication of Telbivudine
For the treatment of chronic hepatitis B in adult and adolescent patients .16 years of age with evidence of viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.
Toxicity of Telbivudine
There is no information on intentional overdose of telbivudine, but one subject experienced an unintentional and asymptomatic overdose. Healthy subjects who received telbivudine doses up to 1800 mg/day for 4 days had no increase in or unexpected adverse events. A maximum tolerated dose for telbivudine has not been determined.
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