Save up -80% on Telbivudine

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Telbivudine

Tyzeka 600 mg tablet

$27.26

tablet

* price without discount in nearest pharmacy. Price may vary.

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Telbivudine volume of distribution

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What is Telbivudine

Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus. Telbivudine is orally administered, with good tolerance, lack of toxicity and no dose-limiting side effects.

Telbivudine mechanism of action

Telbivudine 5’triphosphate inhibits HBV DNA polymerase (reverse transcriptase) by competing with the natural substrate, thymidine 5’triphosphate. This leads to the chain termination of DNA synthesis, thereby inhibiting viral replication. Incorporation of telbivudine 5’triphosphate into viral DNA also causes DNA chain termination, resulting in inhibition of HBV replication. Telbivudine inhibits anticompliment or second-strand DNA.

Dosage forms of Telbivudine

FormRouteStrength
Film-coated tabletOral use600 mg
Oral solutionOral use20 mg/ml
Tabletoral600 mg
Prescription Generics

false

International Brands

Sebivo

Synonyms

1-(2-Deoxy-beta-L-ribofuranosyl)-5-methyluracil 2′-Deoxy-L-thymidine

Manufacturers

Novartis Pharmaceuticals Canada Inc

CAS number

3424-98-4

UNII

2OC4HKD3SF

State

solid

Affected organisms

Hepatitis B virus

Indication of Telbivudine

For the treatment of chronic hepatitis B in adult and adolescent patients .16 years of age with evidence of viral replication and either evidence of persistent elevations in serum aminotransferases (ALT or AST) or histologically active disease.

Toxicity of Telbivudine

There is no information on intentional overdose of telbivudine, but one subject experienced an unintentional and asymptomatic overdose. Healthy subjects who received telbivudine doses up to 1800 mg/day for 4 days had no increase in or unexpected adverse events. A maximum tolerated dose for telbivudine has not been determined.

RX24 Drugs Disclaimer: before buying a Telbivudine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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