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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Telmisartan

Micardis 40 mg tablet



* price without discount in nearest pharmacy. Price may vary.

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Telmisartan volume of distribution

* 500 L

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What is Telmisartan

Telmisartan is an angiotensin II receptor antagonist (ARB) used in the management of hypertension. Generally, angiotensin II receptor blockers (ARBs) such as telmisartan bind to the angiotensin II type 1 (AT1) receptors with high affinity, causing inhibition of the action of angiotensin II on vascular smooth muscle, ultimately leading to a reduction in arterial blood pressure. Recent studies suggest that telmisartan may also have PPAR-gamma agonistic properties that could potentially confer beneficial metabolic effects.

Telmisartan mechanism of action

Telmisartan interferes with the binding of angiotensin II to the angiotensin II AT sub 1 /sub -receptor by binding reversibly and selectively to the receptors in vascular smooth muscle and the adrenal gland. As angiotensin II is a vasoconstrictor, which also stimulates the synthesis and release of aldosterone, blockage of its effects results in decreases in systemic vascular resistance. Telmisartan does not inhibit the angiotensin converting enzyme, other hormone receptors, or ion channels. Studies also suggest that telmisartan is a partial agonist of PPARgamma;, which is an established target for antidiabetic drugs. This suggests that telmisartan can improve carbohydrate and lipid metabolism, as well as control insulin resistance without causing the side effects that are associated with full PPARgamma; activators.

Dosage forms of Telmisartan

Form Route Strength
Tablet Oral use
Tablet Oral use 20 mg
Tablet Oral use 40 mg
Prescription Generics


International Brands

Ach-telmisartan Hctz


4′-((1,4′-Dimethyl-2′-propyl(2,6′-bi-1H-benzimidazol)-1′-yl)methyl)-(1,1′-biphenyl)-2-carboxylic acid 4′-((4-Methyl-6-(1-methyl-2-benzimidazolyl)-2-propyl-1-benzimidazolyl)methyl)-2-biphenylcarboxylic acid


Accord Healthcare Inc

CAS number






Affected organisms

Humans and other mammals

Indication of Telmisartan

Used alone or in combination with other classes of antihypertensives for the treatment of hypertension. Also used in the treatment of diabetic nephropathy in hypertensive patients with type 2 diabetes mellitus, as well as the treatment of congestive heart failure (only in patients who cannot tolerate ACE inhibitors).

Toxicity of Telmisartan

Intravenous LD sub 50 /sub in rats is 150-200 mg/kg in males and 200 to 250 mg/kg in females. Acute oral toxicity is low: no deaths and no changes occurred in rats or dogs at 2000 mg/kg, the highest dose tested. Limited data are available with regard to overdosage in humans. The most likely manifestations of overdosage with telmisartan would be hypotension, dizziness and tachycardia; bradycardia could occur from parasympathetic (vagal) stimulation.

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