Save up -80% on Temazepam
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Restoril
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Restoril coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Temazepam every time. What are you waiting for? Claim your prescription drug card now!
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Temazepam volume of distribution
Mean kinetic variables for temazepam in plasma were: peak plasma level (Cmax), 873 ng ml−1; time of peak, 1·36 h after dosage; volume of distribution, 0·961 kg−1; elimination half‐life, 9·9 h; clearance, 1·16 ml min−1 kg−1. Volume of distribution increased significantly with body weight (r = 0·67, p < 0·001), and Cmax decreased with weight (r = −0·58, p < 0·01). Only 0·2 per cent of the dose was excreted as intact temazepam, and negligible amounts as intact oxazepam.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Temazepam
A benzodiazepine that acts as a gamma-aminobutyric acid modulator and anti-anxiety agent.
Temazepam mechanism of action
Benzodiazepines bind nonspecifically to benzodiazepine receptors, which affects muscle relaxation, anticonvulsant activity, motor coordination, and memory. As benzodiazepine receptors are thought to be coupled to gamma-aminobutyric acid-A (GABA sub A /sub ) receptors, this enhances the effects of GABA by increasing GABA affinity for the GABA receptor. Binding of the inhibitory neurotransmitter GABA to the site opens the chloride channel, resulting in a hyperpolarized cell membrane that prevents further excitation of the cell.
Dosage forms of Temazepam
Humans and other mammals
Indication of Temazepam
For the short-term treatment of insomnia (generally 7-10 days).
Toxicity of Temazepam
Temazepam, like other benzodiazepines, is rarely associated with serum ALT elevations, and clinically apparent liver injury from temazepam is extremely rare, if it occurs at all. There have been no case reports of symptomatic, acute liver injury from temazepam. Cases of clinically apparent liver injury have been reported with other benzodiazepines including alprazolam, chlordiazepoxide, clonazepam, diazepam, flurazepam and triazolam.
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