Save up -80% on Tenecteplase

Note: this is a drug discount program, not an insurance plan.

RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Tenecteplase

Tnkase 50 mg kit



* price without discount in nearest pharmacy. Price may vary.

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Tenecteplase volume of distribution

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What is Tenecteplase

Tissue plasminogen activator (tPA). Tenecteplase is a 527 amino acid glycoprotein developed by introducing the following modifications to the complementary DNA (cDNA) for natural human tPA: a substitution of threonine 103 with asparagine, and a substitution of asparagine 117 with glutamine, both within the kringle 1 domain, and a tetra-alanine substitution at amino acids 296-299 in the protease domain.

Tenecteplase mechanism of action

Tenecteplase binds to fibrin rich clots via the fibronectin finger-like domain and the Kringle 2 domain. The protease domain then cleaves the Arg/Val bond in plasminogen to form plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action.

Dosage forms of Tenecteplase

Form Route Strength
Powder and solvent for solution for injection Intravenous use 10000 units
Powder and solvent for solution for injection Intravenous use 8000 units
Prescription Generics


International Brands



t- PA t-plasminogen activator


Hoffmann La Roche Limited

CAS number






Affected organisms

Humans and other mammals

Indication of Tenecteplase

For treatment of myocardial infarction and lysis of intracoronary emboli

Toxicity of Tenecteplase

RX24 Drugs Disclaimer: before buying a Tenecteplase on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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