Save up -80% on Tenecteplase
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Tenecteplase
Tnkase 50 mg kit
|price without discount in nearest pharmacy. Price may vary.|
We offer free Tenecteplase coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Tenecteplase every time. What are you waiting for? Claim your prescription drug card now!
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Tenecteplase volume of distribution
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Tenecteplase
Tissue plasminogen activator (tPA). Tenecteplase is a 527 amino acid glycoprotein developed by introducing the following modifications to the complementary DNA (cDNA) for natural human tPA: a substitution of threonine 103 with asparagine, and a substitution of asparagine 117 with glutamine, both within the kringle 1 domain, and a tetra-alanine substitution at amino acids 296-299 in the protease domain.
Tenecteplase mechanism of action
Tenecteplase binds to fibrin rich clots via the fibronectin finger-like domain and the Kringle 2 domain. The protease domain then cleaves the Arg/Val bond in plasminogen to form plasmin. Plasmin in turn degrades the fibrin matrix of the thrombus, thereby exerting its thrombolytic action.
Dosage forms of Tenecteplase
|Powder and solvent for solution for injection||Intravenous use||10000 units|
|Powder and solvent for solution for injection||Intravenous use||8000 units|
t- PA t-plasminogen activator
Hoffmann La Roche Limited
Humans and other mammals
Indication of Tenecteplase
For treatment of myocardial infarction and lysis of intracoronary emboli
Toxicity of Tenecteplase
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