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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Terbinafine

Lamisil 1% cream

$2.13

g

* price without discount in nearest pharmacy. Price may vary.

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Terbinafine volume of distribution

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What is Terbinafine

Terbinafine hydrochloride (Lamisil) is a synthetic allylamine antifungal. It is highly lipophilic in nature and tends to accumulate in skin, nails, and fatty tissues. Like other allylamines, terbinafine inhibits ergosterol synthesis by inhibiting the fungal squalene monooxygenase (squalene 2,3-epoxidase), an enzyme that is part of the fungal cell wall synthesis pathway.

Terbinafine mechanism of action

Terbinafine is hypothesized to act by inhibiting squalene monooxygenase, thus blocking the biosynthesis of ergosterol, an essential component of fungal cell membranes. This inhibition also results in an accumulation of squalene, which is a substrate catalyzed to 2,3-oxydo squalene by squalene monooxygenase. The resultant high concentration of squalene and decreased amount of ergosterol are both thought to contribute to terbinafine’s antifungal activity.

Dosage forms of Terbinafine

DrugDosageQuantityPrice
Lamisil Cream1%30g Cream$49.50
Lamisil250mg84 Tablet$230.00
Lamisil Spray1%30mL Spray$44.00
Lamisil Spray1%30mL Spray$44.00
Terbinafine250mg84 Tablet$79.00
Prescription Generics

false

International Brands

Act Terbinafine

Synonyms

(e)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalene methanamine (e)-N-(6,6-Dimethyl-2-hepten-4-ynyl)-N-methyl-1-naphthalenemethylamine

Manufacturers

Actavis Pharma Company

CAS number

91161-71-6

UNII

G7RIW8S0XP

State

solid

Affected organisms

Fungi

Indication of Terbinafine

For the treatment of dermatophyte infections of the toenail or fingernail caused by susceptible fungi. Also for the treatment of tinea capitis (scalp ringworm) and tinea corporis (body ringworm) or tinea cruris (jock itch).

Toxicity of Terbinafine

RX24 Drugs Disclaimer: before buying a Terbinafine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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