Save up -80% on Teriflunomide
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Aubagio
|$6,491||1 package (28 tablets) 14 mg|
|Price with discount in nearest pharmacy. Price may vary.|
We offer free Teriflunomide coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Teriflunomide every time. What are you waiting for? Claim your prescription drug card now!
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Teriflunomide volume of distribution
After a single intravenous dose, the volume of distribution is 11 L.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Teriflunomide
Teriflunomide is the active metabolite of leflunomide, and it acts as an immunomodulatory agent by inhibiting pyrimidine synthesis. It is marketed under the name Aubagio and is indicated for the treatment of multiple sclerosis, specifically relapsing forms. The FDA label states an important warning about the risk of hepatoxicity and teratogenicity for patients using teriflunomide.
Teriflunomide mechanism of action
The exact mechanism by which teriflunomide acts in MS is not known. What is known is that teriflunomide prevents pyrimidine synthesis by inhibiting the mitochondrial enzyme dihydroorotate dehydrogenase, and this may be involved in its immunomodulatory effect in MS.
Dosage forms of Teriflunomide
|Film-coated tablet||Oral use||14 mg|
|Tablet, film coated||oral||14 mg/1|
(Z)-2-Cyano-alpha,alpha,alpha-trifluoro-3-hydroxy-P-crotonotoluidide a 77-1726
Humans and other mammals
Indication of Teriflunomide
Used in the treatment of relapsing forms of multiple sclerosis (MS).
Toxicity of Teriflunomide
Teriflunomide is contraindicated in pregnant women or women of childbearing age due to the risk of teratogenicity. Teriflunomide is also contraindicated in severe hepatic impairment due to reports of hepatotoxicity, hepatic failure, and death.
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