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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Tesamorelin

$

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Tesamorelin volume of distribution

9.4 3.1 L/kg in healthy subjects. 10.5 6.1 L/kg in HIV-infected patients.

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What is Tesamorelin

Tesamorelin is a stabilized synthetic peptide analogue of the hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) indicated for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy. Lipodystrophy is a metabolic condition characterized by insulin resistance, fat redistribution, and hyperlipidemia associated with antiretroviral therapy for HIV infection.

Tesamorelin mechanism of action

By acting on the pituitary cells in the brain, tesamorelin stimulates production and release of the endogenous hormone (hGRF). Tesamorelin therapy predisposes the patient to glucose intolerance and can also increase the risk of type 2 diabetes, so the drug is contraindicated in pregnancy.

Dosage forms of Tesamorelin

FormRouteStrength
Kitsubcutaneous
Kit; powder for solutionsubcutaneous1 mg
Kit; powder for solutionsubcutaneous2 mg
Prescription Generics

false

International Brands

Egrifta

Synonyms

GHRH(1-44) N-[(3E)-1-oxo-3-hexenyl]Somatoliberin (human pancreatic islet)

Manufacturers

EMD Serono, Inc.

CAS number

218949-48-5

UNII

MQG94M5EEO

State

solid

Affected organisms

Humans and other mammals

Indication of Tesamorelin

Tesamorelin acetate is a synthetic analogue of human hypothalamic Growth Hormone Releasing Factor (hGRF) indicated to induce and maintain a reduction of excess abdominal fat in HIV-infected patients with lipodystrophy.

Toxicity of Tesamorelin

Diarrhea, congestive heart failure, peripheral neuropathy, and loss of mobility were the four serious adverse events reported during the clinical studies

RX24 Drugs Disclaimer: before buying a Tesamorelin on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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