Save up -80% on Theophylline
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Elixophyllin
|$111.37||150 ml 80mg/15ml elixir|
|price without discount in nearest pharmacy. Price may vary.|
We offer free Elixophyllin coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Theophylline every time. What are you waiting for? Claim your prescription drug card now!
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Theophylline volume of distribution
Theophylline is distributed in the extracellular fluid, in the placenta, in the mother’s milk and in the central nervous system. The volume of distribution is 0.5 L/kg. The protein binding is 40%.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Theophylline
A methylxanthine derivative from tea with diuretic, smooth muscle relaxant, bronchial dilation, cardiac and central nervous system stimulant activities. Mechanistically, theophylline acts as a phosphodiesterase inhibitor, adenosine receptor blocker, and histone deacetylase activator. Theophylline is marketed under several brand names such as Uniphyl and Theochron, and it is indicated mainly for asthma, bronchospasm, and COPD.
Theophylline mechanism of action
Theophylline relaxes the smooth muscle of the bronchial airways and pulmonary blood vessels and reduces airway responsiveness to histamine, methacholine, adenosine, and allergen. Theophylline competitively inhibits type III and type IV phosphodiesterase (PDE), the enzyme responsible for breaking down cyclic AMP in smooth muscle cells, possibly resulting in bronchodilation. Theophylline also binds to the adenosine A2B receptor and blocks adenosine mediated bronchoconstriction. In inflammatory states, theophylline activates histone deacetylase to prevent transcription of inflammatory genes that require the acetylation of histones for transcription to begin.
Dosage forms of Theophylline
|Uniphyl SR||400mg||50 Extended Release 24hour Tablet||$59.00|
|Uniphyl SR||600mg||50 Extended Release 24hour Tablet||$67.00|
|Uniphyl SR||600mg||100 Extended Release 24hour Tablet||$123.00|
|Theophylline||400mg||100 Extended Release 24hour Tablet||$84.00|
|Theophylline||600mg||100 Extended Release 24hour Tablet||$92.00|
|Theophylline SR||100mg||100 SR Tablet||$36.00|
|Theophylline SR||200mg||100 SR Tablet||$39.00|
|Theophylline SR||300mg||100 SR Tablet||$42.00|
Humans and other mammals
Indication of Theophylline
For the treatment of the symptoms and reversible airflow obstruction associated with chronic asthma and other chronic lung diseases, such as emphysema and chronic bronchitis.
Toxicity of Theophylline
Symptoms of overdose include seizures, arrhythmias, and GI effects.
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