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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Thiamine

Thiamiject 100 mg/ml

$1.24

ml

* price without discount in nearest pharmacy. Price may vary.

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What is Thiamine

Thiamine or thiamin, also known as vitamin B1, is a colorless compound with the chemical formula C12H17N4OS. It is soluble in water and insoluble in alcohol. Thiamine decomposes if heated. Thiamine was first discovered by Umetaro Suzuki in Japan when researching how rice bran cured patients of Beriberi. Thiamine plays a key role in intracellular glucose metabolism and it is thought that thiamine inhibits the effect of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine plays an important role in helping the body convert carbohydrates and fat into energy. It is essential for normal growth and development and helps to maintain proper functioning of the heart and the nervous and digestive systems. Thiamine cannot be stored in the body; however, once absorbed, the vitamin is concentrated in muscle tissue.

Thiamine mechanism of action

It is thought that the mechanism of action of thiamine on endothelial cells is related to a reduction in intracellular protein glycation by redirecting the glycolytic flux. Thiamine is mainly the transport form of the vitamin, while the active forms are phosphorylated thiamine derivatives. There are five known natural thiamine phosphate derivatives: thiamine monophosphate (ThMP), thiamine diphosphate (ThDP), also sometimes called thiamine pyrophosphate (TPP), thiamine triphosphate (ThTP), and the recently discovered adenosine thiamine triphosphate (AThTP), and adenosine thiamine diphosphate. Each derivative has unique functions, however, most are involved as coenzymes.

Dosage forms of Thiamine

DrugDosageQuantityPrice
Thiamine100mg/mL10mL Vial$39.00
Thiamine100mg100 Tablet$29.0
Vitamin B1 by Jamieson100mg100 Tablet$30.10
Prescription Generics

false

International Brands

Acti-MN + B1 + C Caplet

Synonyms

3-(4-AMINO-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium Aneurin

Manufacturers

Acti Form Ltd.

CAS number

59-43-8

UNII

X66NSO3N35

State

solid

Affected organisms

Humans and other mammals

Indication of Thiamine

For the treatment of thiamine and niacin deficiency states, Korsakov’s alcoholic psychosis, Wernicke-Korsakov syndrome, delirium, and peripheral neuritis.

Toxicity of Thiamine

Thiamine toxicity is uncommon; as excesses are readily excreted, although long-term supplementation of amounts larger than 3 gram have been known to cause toxicity. Oral mouse LD sub 50 /sub = 8224 mg/kg, oral rat LD sub 50 /sub = 3710 mg/kg.

RX24 Drugs Disclaimer: before buying a Thiamine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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