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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Thioridazine

Thioridazine HCl 150 mg tablet

$1.01

tablet

* price without discount in nearest pharmacy. Price may vary.

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Thioridazine volume of distribution

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What is Thioridazine

A phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p618)

Thioridazine mechanism of action

Thioridazine blocks postsynaptic mesolimbic dopaminergic D1 and D2 receptors in the brain; blocks alpha-adrenergic effect, depresses the release of hypothalamic and hypophyseal hormones and is believed to depress the reticular activating system thus affecting basal metabolism, body temperature, wakefulness, vasomotor tone, and emesis.

Dosage forms of Thioridazine

FormRouteStrength
Liquidoral30 mg
Suspensionoral10 mg
Tabletoral100 mg
Prescription Generics

false

International Brands

Mellaril

Synonyms

10-(2-(1-Methyl-2-piperidyl)ethyl)-2-methylsulfanyl-phenothiazine 2-Methylmercapto-10-(2-(N-methyl-2-piperidyl)ethyl)phenothiazine

Manufacturers

Novartis Pharmaceuticals Canada Inc

CAS number

50-52-2

UNII

N3D6TG58NI

State

solid

Affected organisms

Humans and other mammals

Indication of Thioridazine

For the treatment of schizophrenia and generalized anxiety disorder.

Toxicity of Thioridazine

LD sub50 /sub=956-1034 mg/kg (Orally in rats); Agitation, blurred vision, coma, confusion, constipation, difficulty breathing, dilated or constricted pupils, diminished flow of urine, dry mouth, dry skin, excessively high or low body temperature, extremely low blood pressure, fluid in the lungs, heart abnormalities, inability to urinate, intestinal blockage, nasal congestion, restlessness, sedation, seizures, shock

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