Save up -80% on Thyrotropin Alfa

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Thyrogen

$2,952.551 carton (2 vials) 0.9mg/ml
price without discount in nearest pharmacy. Price may vary.

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We offer free Thyrogen coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Thyrotropin Alfa every time. What are you waiting for? Claim your prescription drug card now!

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Thyrotropin Alfa volume of distribution

The pharmacokinetics of Thyrogen were studied in 16 patients with well-differentiated thyroid cancer given a single 0.9 mg IM dose. Mean peak concentrations of 116 ± 38 mU/L were reached between 3 and 24 hours after injection (median of 10 hours). The mean apparent elimination half-life was 25 ± 10 hours.

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2018 Statistics

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Discount Cards 16,000+

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Clients Benefit 29%

savings

Total savings $4,735,080

What is Thyrotropin Alfa

Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of thyroid cancer. It is a heterodimeric glycoprotein comprised of two non-covalently linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites and a beta subunit of 112 residues containing one N-linked glycosylation site. The alpha subunit is nearly identical to that of human chorionic gonadotropin (hCG), luteinizing hormone (LH), and follicle-stimulating hormone (FSH). The alpha subunit is thought to be the effector region responsible for stimulation of adenylate cyclase (involved the generation of cAMP). The beta subunit (TSHB) is unique to TSH, and therefore determines its receptor specificity. The amino acid sequence of thyrotropin alfa is identical to that of human pituitary thyroid stimulating hormone.

Thyrotropin Alfa mechanism of action

Thyrotropin Alfa binds to the thyrotropin receptors found on any residual thyroid cells or tissues. This stimulates radioactive iodine uptake for better radiodiagnostic imaging.

Dosage forms of Thyrotropin Alfa

FormRouteStrength
Injection, powder, for solutionintramuscular.9 mg/mL
Kit
Powder for solutionintramuscular0.9 mg

Prescription Generics

false

International Brands

Thyrogen

Synonyms

rTSH Thyroid stimulating hormone

Manufacturers

Genzyme Canada A Division Of Sanofi Aventis Canada Inc

CAS number

194100-83-9

UNII

AVX3D5A4LM

State

liquid

Affected organisms

Humans and other mammals

Indication of Thyrotropin Alfa

For detection of residueal or recurrent thyroid cancer

Toxicity of Thyrotropin Alfa

No difference in efficacy and toxicity between adult and geriatric patients. No studies in lactating women, pregnant women and pediatrics. Cautionary administration is advised.

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