Save up -80% on Thyrotropin Alfa

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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Thyrotropin Alfa

Thyrogen 1.1 mg vial



* price without discount in nearest pharmacy. Price may vary.

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Thyrotropin Alfa volume of distribution

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What is Thyrotropin Alfa

Thyrotropin alfa is a recombinant form of thyroid stimulating hormone used in performing certain tests in patients who have or have had thyroid cancer. It is also used along with a radioactive agent to destroy remaining thyroid tissue in certain patients who have had their thyroid gland removed because of thyroid cancer. It is a heterodimeric glycoprotein comprised of two non-covalently linked subunits, an alpha subunit of 92 amino acid residues containing two N-linked glycosylation sites and a beta subunit of 112 residues containing one N-linked glycosylation site. The alpha subunit is nearly identical to that of human chorionic gonadotropin (hCG), luteinizing hormone (LH), and follicle-stimulating hormone (FSH). The alpha subunit is thought to be the effector region responsible for stimulation of adenylate cyclase (involved the generation of cAMP). The beta subunit (TSHB) is unique to TSH, and therefore determines its receptor specificity. The amino acid sequence of thyrotropin alfa is identical to that of human pituitary thyroid stimulating hormone.

Thyrotropin Alfa mechanism of action

Thyrotropin Alfa binds to the thyrotropin receptors found on any residual thyroid cells or tissues. This stimulates radioactive iodine uptake for better radiodiagnostic imaging.

Dosage forms of Thyrotropin Alfa

Injection, powder, for solutionintramuscular.9 mg/mL
Powder for solutionintramuscular0.9 mg
Prescription Generics


International Brands



rTSH Thyroid stimulating hormone


Genzyme Canada A Division Of Sanofi Aventis Canada Inc

CAS number






Affected organisms

Humans and other mammals

Indication of Thyrotropin Alfa

For detection of residueal or recurrent thyroid cancer

Toxicity of Thyrotropin Alfa

No difference in efficacy and toxicity between adult and geriatric patients. No studies in lactating women, pregnant women and pediatrics. Cautionary administration is advised.

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