Save up -80% on Ticlopidine

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Ticlid

$1.86tablet
price without discount in nearest pharmacy. Price may vary.

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We offer free Ticlopidine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Ticlopidine every time. What are you waiting for? Claim your prescription drug card now!

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Ticlopidine volume of distribution

The volume of distribution was not quantified.

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About RX24Drugs

2018 Statistics

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Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Ticlopidine

Ticlopidine is an effective inhibitor of platelet aggregation. It is a prodrug that is metabolised to an active form, which blocks the ADP receptor that is involved in GPIIb/IIIa receptor activation leading to platelet aggregation. Ticlopidine is marketed under the brand name Ticlid and is indicated for patients who cannot take aspirin or in whom aspirin has not worked to prevent a thrombotic stroke. The FDA label includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and agranulocytosis, so it is necessary to monitor patients’ WBC and platelets when they are taking ticlopidine.

Ticlopidine mechanism of action

The active metabolite of ticlopidine prevents binding of adenosine diphosphate (ADP) to its platelet receptor, impairing the ADP-mediated activation of the glycoprotein GPIIb/IIIa complex. It is proposed that the inhibition involves a defect in the mobilization from the storage sites of the platelet granules to the outer membrane. No direct interference occurs with the GPIIb/IIIa receptor. As the glycoprotein GPIIb/IIIa complex is the major receptor for fibrinogen, its impaired activation prevents fibrinogen binding to platelets and inhibits platelet aggregation. By blocking the amplification of platelet activation by released ADP, platelet aggregation induced by agonists other than ADP is also inhibited by the active metabolite of ticlopidine.

Dosage forms of Ticlopidine

FormRouteStrength
Tabletoral250 mg
Tablet, film coatedoral250 mg/1

Prescription Generics

false

International Brands

Alti-ticlopidine – Tab 250mg

Synonyms

Ticlopidina Ticlopidinum

Manufacturers

Altimed Pharma Inc.

CAS number

55142-85-3

UNII

OM90ZUW7M1

State

solid

Affected organisms

Humans and other mammals

Indication of Ticlopidine

Used in patients, who have had a stroke or stroke precursors and who cannot take aspirin or aspirin has not worked, to try to prevent another thrombotic stroke.

Toxicity of Ticlopidine

Single oral doses of ticlopidine at 1600 mg/kg and 500 mg/kg were lethal to rats and mice, respectively. Symptoms of acute toxicity were GI hemorrhage, convulsions, hypothermia, dyspnea, loss of equilibrium and abnormal gait. The FDA label includes a black-box warning of neutropenia, aplastic anemia, thrombotic thrombocytopenia purpura, and agranulocytosis, so it is necessary to monitor patients’ WBC and platelets when they are taking ticlopidine.

RX24 Drugs Disclaimer: before buying a Ticlopidine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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