Save up -80% on Timolol

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Timolol

Apo-Timop 0.25 % Solution

$1.62

ml

* price without discount in nearest pharmacy. Price may vary.

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Timolol volume of distribution

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What is Timolol

A beta-adrenergic antagonist similar in action to propranolol. The levo-isomer is the more active. Timolol has been proposed as an antihypertensive, antiarrhythmic, antiangina, and antiglaucoma agent. It is also used in the treatment of migraine disorders and tremor.

Timolol mechanism of action

Like propranolol and nadolol, timolol competes with adrenergic neurotransmitters such as catecholamines for binding at beta(1)-adrenergic receptors in the heart and vascular smooth muscle and beta(2)-receptors in the bronchial and vascular smooth muscle. Beta(1)-receptor blockade results in a decrease in resting and exercise heart rate and cardiac output, a decrease in both systolic and diastolic blood pressure, and, possibly, a reduction in reflex orthostatic hypotension. Beta(2)-blockade results in an increase in peripheral vascular resistance. The exact mechanism whereby timolol reduces ocular pressure is still not known. The most likely action is by decreasing the secretion of aqueous humor.

Dosage forms of Timolol

DrugDosageQuantityPrice
Timolol Maleate5mg100 Tablet$42.00
Timolol Maleate20mg100 Tablet$72.00
Timolol Maleate0.25%5mL Eye Gel$40.0
Timolol Maleate0.50%5mL Eye Gel$51.00
Timoptic Eyedrops0.50%20mL Eye drops$79.00
Timoptic XE Ophthalmic Gel0.50%15mL$81.00
Timoptic Ocudose Preservative Free0.50%90ds Eye drops$366.00
Duotrav0.5/0.004%10mL$155.00
Combigan0.2/0.5%15mL Eye Drops$33.90
Dorzolamide/Timolol2/0.5%10mL Eye Drops$59.00
Cosopt2/0.5%10mL Eye Solution$79.50
Prescription Generics

false

International Brands

Act Dorzotimolol

Synonyms

(S)-1-(tert-butylamino)-3-((4-morpholin-4-yl-1,2,5-thiadiazol-3-yl)oxy)propan-2-ol Timolol

Manufacturers

Actavis Pharma Company

CAS number

26839-75-8

UNII

5JKY92S7BR

State

solid

Affected organisms

Humans and other mammals

Indication of Timolol

In its oral form it is used to treat high blood pressure and prevent heart attacks, and occasionally to prevent migraine headaches. In its opthalmic form it is used to treat open-angle and occasionally secondary glaucoma.

Toxicity of Timolol

LD sub 50 /sub =1190 mg/kg (oral, mice), LD sub 50 /sub =900 mg/kg (oral, rat). Symptoms of overdose include drowsiness, vertigo, headache, and atriventricular block.

RX24 Drugs Disclaimer: before buying a Timolol on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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