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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Tiotropium

Spiriva 18 mcg Capsule

$2.2

capsule

* price without discount in nearest pharmacy. Price may vary.

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Tiotropium volume of distribution

* 32 L/kg

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What is Tiotropium

Tiotropium is a long-acting, 24 hour, anticholinergic bronchodilator used in the management of chronic obstructive pulmonary disease (COPD). Tiotropium is a muscarinic receptor antagonist, on topical application it acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation, thus producing a bronchodilatory effect.

Tiotropium mechanism of action

Tiotropium is a muscarinic receptor antagonist, often referred to as an antimuscarinic or anticholinergic agent. Although it does not display selectivity for specific muscarinic receptors, on topical application it acts mainly on M3 muscarinic receptors located in the airways to produce smooth muscle relaxation, thus producing a bronchodilatory effect.

Dosage forms of Tiotropium

DrugDosageQuantityPrice
Spiriva Handihaler18mcg30 Capsule Inhaler$44.70
Spiriva Handihaler18mcg90 Capsule Inhaler$77.50
Spiriva Respimat2.5mcg60ds Respimat Inhaler$120.00
Spiriva Respimat2.5mcg180ds Respimat Inhaler$340.00
Tiotropium bromide18mcg90 Rotacaps$37.10
Stiolto Respimat2.5mcg/2.5mcg60puffs Respimat Inhaler$190.00
Stiolto Respimat2.5mcg/2.5mcg120puffs Respimat Inhaler$370.00
Prescription Generics

false

International Brands

Inspiolto Respimat

Synonyms

Manufacturers

Boehringer Ingelheim (Canada) Ltd Ltee

CAS number

186691-13-4

UNII

0EB439235F

State

solid

Affected organisms

Humans and other mammals

Indication of Tiotropium

Used in the management of chronic obstructive pulmonary disease (COPD).

Toxicity of Tiotropium

No mortality was observed at inhalation tiotropium doses up to 32.4 mg/kg in mice, 267.7 mg/kg in rats, and 0.6 mg/kg in dogs. These doses correspond to 7,300, 120,000, and 850 times the recommended human daily dose on a mg/m2 basis, respectively.

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