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Price of Tositumomab
Bexxar 14 mg/ml dosimetric
* price without discount in nearest pharmacy. Price may vary.
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Tositumomab volume of distribution
What is Tositumomab
Murine IgG2a lambda monoclonal antibody against CD20 antigen (2 heavy chains of 451 residues, 2 lambda chains of 220 residues). It is produced in an antibiotic-free culture of mammalian cells. It can be covalently linked to Iodine 131 (a radioactive isotope of iodine).
Tositumomab mechanism of action
Binds to the CD20 antigen which is found on mature B lymphocytes. The antibody binding appears to induce apoptosis, complement-dependent cytotoxicity and cell death through ionizing radiation.
Dosage forms of Tositumomab
|Solution; kit||intravenous||14 mg|
Ig gamma-1 chain C region
Humans and other mammals
Indication of Tositumomab
For treatment of non-Hodgkin’s lymphoma (CD20 positive, follicular)
Toxicity of Tositumomab
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