Save up -80% on Trametinib

Note: this is a drug discount program, not an insurance plan.
RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Mekinist

$3,301.4730 tablets (0.5mg)
Price with discount in nearest pharmacy. Price may vary.

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We offer free Trametinib coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Trametinib every time. What are you waiting for? Claim your prescription drug card now!

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Trametinib volume of distribution

Trametinib is administered orally. It is highly bound to plasma proteins (97.4%) and has an apparent volume of distribution of 214 liters (L).

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2018 Statistics

discount card

Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Trametinib

Trametinib dimethyl sulfoxide is a kinase inhibitor. Each 1-mg tablet contains 1.127 mg trametinib dimethyl sulfoxide equivalent to 1 mg of trametinib non-solvated parent. FDA approved on May 29, 2013.

Trametinib mechanism of action

Trametinib is a reversible, allosteric inhibitor of mitogen-activated extracellular signal regulated kinase 1 (MEK1) and MEK2 activation and of MEK1 and MEK2 kinase activity. MEK proteins are upstream regulators of the extracellular signal-related kinase (ERK) pathway, which promotes cellular proliferation. Trametinib helps with melanoma with the BRAF V600E or V600K as the mutation results in the constitutive activation of the BRAF pathway which includes MEK1 and MEK2.

Dosage forms of Trametinib

Mekinist0.5mg30 tablets$2,626
Mekinist2mg30 tablets$10,209

Prescription Generics


International Brands



GSK 1120212 JTP 74057


Glaxo Smith Kline Llc

CAS number






Affected organisms

Humans and other mammals

Indication of Trametinib

Trametinib is indicated for the treatment of unresectable or metastatic melanoma with BRAF V600E or V600K mutations, as detected by an FDA-approved test.

Toxicity of Trametinib

Most common adverse reactions ( 20%) for trametinib include rash, diarrhea, and lymphedema.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Trametinib on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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