Save up -80% on Tranylcypromine

Note: this is a drug discount program, not an insurance plan.

RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Tranylcypromine

Tranylcypromine sulf 10 mg tablet

$1.25

tablet

* price without discount in nearest pharmacy. Price may vary.

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Tranylcypromine volume of distribution

1.1-5.7 L/kg

About RX24Drugs

Discount Cards 16,000+

Clients Benefit 29%

Total savings $4,735,080

What is Tranylcypromine

A propylamine formed from the cyclization of the side chain of amphetamine. This monoamine oxidase inhibitor is effective in the treatment of major depression, dysthymic disorder, and atypical depression. It also is useful in panic and phobic disorders. (From AMA Drug Evaluations Annual, 1994, p311)

Tranylcypromine mechanism of action

Tranylcypromine irreversibly and nonselectively inhibits monoamine oxidase (MAO). Within neurons, MAO appears to regulate the levels of monoamines released upon synaptic firing. Since depression is associated with low levels of monoamines, the inhibition of MAO serves to ease depressive symptoms, as this results in an increase in the concentrations of these amines within the CNS.

Dosage forms of Tranylcypromine

FormRouteStrength
Tabletoral10 mg
Tablet, film coatedoral10 mg/1
Tabletoral10 mg/1
Prescription Generics

false

International Brands

Parnate

Synonyms

Parnate Tranilcipromina

Manufacturers

Glaxosmithkline Inc

CAS number

155-09-9

UNII

3E3V44J4Z9

State

solid

Affected organisms

Humans and other mammals

Indication of Tranylcypromine

For the treatment of major depressive episode without melancholia.

Toxicity of Tranylcypromine

In overdosage, some patients exhibit insomnia, restlessness and anxiety, progressing in severe cases to agitation, mental confusion and incoherence. Hypotension, dizziness, weakness and drowsiness may occur, progressing in severe cases to extreme dizziness and shock. A few patients have displayed hypertension with severe headache and other symptoms. Rare instances have been reported in which hypertension was accompanied by twitching or myoclonic fibrillation of skeletal muscles with hyperpyrexia, sometimes progressing to generalized rigidity and coma.

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