Save up -80% on Treprostinil
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
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2019 Price of Orenitram
|price without discount in nearest pharmacy. Price may vary.|
We offer free Orenitram coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Treprostinil every time. What are you waiting for? Claim your prescription drug card now!
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Treprostinil volume of distribution
Remodulin when administered chronically as a subcutaneous infusion is completely absorbed and has a mean apparent elimination half-life of 3 hours compared to 45 minutes when administered intravenously. The mean volume of distribution and plasma clearance for treprostinil are 1.1 L/kg and 589 mL/kg/hr, respectively.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Treprostinil
Treprostinil is a synthetic analogue of prostacyclin, used to treat pulmonary hypertension. Treprostinil is marketed as Remodulin reg;. (Wikipedia)
Treprostinil mechanism of action
The major pharmacological actions of treprostinil are direct vasodilation of pulmonary and systemic arterial vascular beds and inhibition of platelet aggregation. In addition to treprostinil’s direct vasodilatory effects, it also inhibits inflammatory cytokine. As a synthetic analogue of prostacyclin, it binds to the prostacyclin receptor, which subsequently induces the aforementioned downstream effects.
Dosage forms of Treprostinil
|Tablet, extended release||oral||.125 mg/1|
|Tablet, extended release||oral||.25 mg/1|
|Tablet, extended release||oral||1 mg/1|
(1R,2R,3aS,9aS)-((2,3,3a,4,9,9a-hexahydro-2-hydroxy- 1-((3S)-3-hydroxyoctyl)-1H-benz(f)inden-5-yl) oxy)acetic acid (((1R,2R,3aS,9aS)-2-Hydroxy-1-((3S)-3-hydroxyoctyl)-2,3,3a,4,9,9a-hexahydro-1H-cyclopenta(b)naphtalen-5-yl)oxy)acetic acid
United Therapeutics Corp.
Humans and other mammals
Indication of Treprostinil
For use as a continuous subcutaneous infusion or intravenous infusion (for those not able to tolerate a subcutaneous infusion) for the treatment of pulmonary arterial hypertension in patients with NYHA Class II-IV symptoms to diminish symptoms associated with exercise.
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