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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Trihexyphenidyl

Apo-Trihex 2 mg Tablet

$0.04

tablet

* price without discount in nearest pharmacy. Price may vary.

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Trihexyphenidyl volume of distribution

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What is Trihexyphenidyl

One of the centrally acting muscarinic antagonists used for treatment of parkinsonian disorders and drug-induced extrapyramidal movement disorders and as an antispasmodic.

Trihexyphenidyl mechanism of action

Trihexyphenidyl is a selective M1 muscarinic acetylcholine receptor antagonist. It is able to discriminate between the M1 (cortical or neuronal) and the peripheral muscarinic subtypes (cardiac and glandular). Trihexyphenidyl partially blocks cholinergic activity in the CNS, which is responsible for the symptoms of Parkinson‘s disease. It is also thought to increase the availability of dopamine, a brain chemical that is critical in the initiation and smooth control of voluntary muscle movement.

Dosage forms of Trihexyphenidyl

FormRouteStrength
Elixiroral2 mg
Elixiroral0.4 mg
Tabletoral2 mg
Prescription Generics

false

International Brands

Aparkane Tab 2mg

Synonyms

(RS)-1-cyclohexyl-1-phenyl-3-(1-piperidyl)propan-1-ol Apo-trihex

Manufacturers

Icn Canada Ltd.

CAS number

144-11-6

UNII

6RC5V8B7PO

State

solid

Affected organisms

Humans and other mammals

Indication of Trihexyphenidyl

Indicated for the treatment of parkinson’s disease and extrapyramidal reactions caused by drugs.

Toxicity of Trihexyphenidyl

Symptoms of overdose include mydriasis, dryness of mucous membranes, red face, atonic states of bowels and bladder, and hyperthermia in high doses. Central consequences are agitation, confusion, and hallucinations. An untreated overdose may be fatal, particular in children. Premortal signs are respiratory depression and cardiac arrest.

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