Save up -80% on Trimethobenzamide
|Note: this is a drug discount program, not an insurance plan.|
|RX BIN: 015558||RX PCN: HT||Group ID: DDN6600||Card Holder ID: DDN6600|
|Pharmacists and Patients support.|
2019 Price of Tigan
|$55.1||90 capsules/300 mg|
|Price with discount in nearest pharmacy. Price may vary.|
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Trimethobenzamide volume of distribution
Tigecycline had a large volume of distribution (7 to 10 liters/kg), indicating extensive distribution into the tissues. Food increased the maximum tolerated single-dose from 100 to 200 mg, but the duration of infusion did not affect tolerability. Side effects, mainly nausea and vomiting, which are common to the tetracycline class of antimicrobial agents, were seen in these studies.
Discount Cards 16,000+
Clients Benefit 29%
Total savings $4,735,080
What is Trimethobenzamide
Trimethobenzamide is a novel antiemetic which prevents nausea and vomiting in humans. Its actions are unclear but most likely involves the chemoreceptor trigger zone (CTZ). In dogs pretreated with trimethobenzamide HCl, the emetic response to apomorphine is inhibited, while little or no protection is afforded against emesis induced by intragastric copper sulfate.
Trimethobenzamide mechanism of action
The mechanism of action of trimethobenzamide as determined in animals is obscure, but may involve the chemoreceptor trigger zone (CTZ), an area in the medulla oblongata through which emetic impulses are conveyed to the vomiting center; direct impulses to the vomiting center apparently are not similarly inhibited.
Dosage forms of Trimethobenzamide
|Injection, solution||intramuscular||100 mg/mL|
Pfizer Laboratories Div Pfizer Inc
Humans and other mammals
Indication of Trimethobenzamide
For the treatment of postoperative nausea and vomiting and for nausea associated with gastroenteritis.
Toxicity of Trimethobenzamide
Oral LD sub50 /sub in mice is 1600 mg/kg.
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