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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Ulobetasol

Halobetasol prop 0.05% cream

$1.8g
price without discount in nearest pharmacy. Price may vary.

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Ulobetasol volume of distribution

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About RX24Drugs

2018 Statistics

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Discount Cards 16,000+

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Clients Benefit 29%

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Total savings $4,735,080

What is Ulobetasol

Ulobetasol (as ulobetasol propionate) is thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. It is used for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Ulobetasol mechanism of action

Halobetasol propionate is thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2. The initial interaction, however, is due to the drug binding to the cytosolic glucocorticoid receptor. After binding the receptor the newly formed receptor-ligand complex translocates itself into the cell nucleus, where it binds to many glucocorticoid response elements (GRE) in the promoter region of the target genes. The DNA bound receptor then interacts with basic transcription factors, causing the increase in expression of specific target genes.

Dosage forms of Ulobetasol

FormRouteStrength
Creamtopical.5 mg/g
Ointmenttopical.5 mg/g
Lotiontopical.5 mg/g

Prescription Generics

true

International Brands

Halobetasol Propionate

Synonyms

21-chloro diflorasone Halobetasol

Manufacturers

E. Fougera CO., A division of Fougera Pharmaceuticals Inc.

CAS number

98651-66-2

UNII

9P6159HM7T

State

solid

Affected organisms

Humans and other mammals

Indication of Ulobetasol

For the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.

Toxicity of Ulobetasol

RX24 Drugs Disclaimer: before buying a Ulobetasol on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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