Save up -80% on Urofollitropin

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Urofollitropin

Bravelle 75 unit vial

$93.85

vial

* price without discount in nearest pharmacy. Price may vary.

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Urofollitropin volume of distribution

Time to peak in plasma: ; IM: 17 hours (single dose), 11 hours (multiple doses) ; SubQ: 21 hours (single dose), 10 hours (multiple doses)

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What is Urofollitropin

Urofollitropin is a purified form of follicle-stimulating hormone (FSH) that is manufactured by extraction from human urine and then purified. It consists of two non-covalently linked, non-identical glycoproteins designated as the alpha- and beta- subunits. The alpha- and beta- subunits have 92 and 111 amino acids. The alpha subunit is glycosylated at Asn 51 and Asn 78 while the beta subunit is glycosylated at Asn 7 and Asn 24. Urofollitropin is important in the development of follicles produced by the ovaries. Given by subcutaneous injection, it is used in combination with human chorionic gonadotropin (hCG) to assist in ovulation and fertility. Urofollitropin may also be used to cause the ovary to produce several follicles, which can then be harvested for use in gamete intrafallopian transfer (GIFT) or in vitro fertilization (IVF).

Urofollitropin mechanism of action

FSH binds to the follicle stimulating hormone receptor which is a G-coupled transmembrane receptor. Binding of the FSH to its receptor seems to induce phosphorylation and activation of the PI3K (Phosphatidylinositol-3-kinase) and Akt signaling pathway, which is known to regulate many other metabolic and related survival/maturation functions in cells.

Dosage forms of Urofollitropin

DrugDosageQuantityPrice
Fostimon75IU10 Vials$276.00
Fostimon150IU10 Vials$476.00
Bravelle Injection75IU5vials Vials$426.00
Bravelle Injection75IU15vials Vials$1,254.00
Prescription Generics

false

International Brands

Bravelle

Synonyms

Follicle Stimulating Hormone Follicle-stimulating hormone beta subunit

Manufacturers

Ferring Inc

CAS number

146479-72-3

UNII

076WHW89TW

State

liquid

Affected organisms

Humans and other mammals

Indication of Urofollitropin

For treatment of female infertility

Toxicity of Urofollitropin

RX24 Drugs Disclaimer: before buying a Urofollitropin on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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