Save up -80% on Vandetanib

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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Vandetanib


* price without discount in nearest pharmacy. Price may vary.

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Vandetanib volume of distribution

Vd of about 7450 L.

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What is Vandetanib

Vandetanib is an oral once-daily kinase inhibitor of tumour angiogenesis and tumour cell proliferation with the potential for use in a broad range of tumour types. On April 6 2011, vandetanib was approved by the FDA to treat nonresectable, locally advanced, or metastatic medullary thyroid cancer in adult patients.

Vandetanib mechanism of action

ZD-6474 is a potent and selective inhibitor of VEGFR (vascular endothelial growth factor receptor), EGFR (epidermal growth factor receptor) and RET (REarranged during Transfection) tyrosine kinases. VEGFR- and EGFR-dependent signalling are both clinically validated pathways in cancer, including non-small-cell lung cancer (NSCLC). RET activity is important in some types of thyroid cancer, and early data with vandetanib in medullary thyroid cancer has led to orphan-drug designation by the regulatory authorities in the USA and EU.

Dosage forms of Vandetanib

Film-coated tabletOral use100 mg
Film-coated tabletOral use300 mg
Tabletoral100 mg
Prescription Generics


International Brands



4-BROMO-2-fluoro-N-[(4e)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazolin-4(1H)-ylidene]aniline 4-quinazolinamine, N-(4-bromo-2-fluorophenyl)-6-methoxy-7-[(1-methyl-4-piperidinyl)methoxy]-


Genzyme Canada A Division Of Sanofi Aventis Canada Inc

CAS number






Affected organisms

Humans and other mammals

Indication of Vandetanib

Vandetanib is currently approved as an alternative to local therapies for both unresectable and disseminated disease. Because Vandetanib can prolong the Q-T interval, it is contraindicated for use in patients with serious cardiac complications such as congenital long QT syndrome and uncompensated heart failure.

Toxicity of Vandetanib

RX24 Drugs Disclaimer: before buying a Vandetanib on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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