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Price of Vasopressin
Vasopressin 20 unit/ml vial
* price without discount in nearest pharmacy. Price may vary.
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Vasopressin volume of distribution
What is Vasopressin
Antidiuretic hormone, also known as vasopressin, is a nine amino acid peptide secreted from the posterior pituitary. Antidiuretic hormone binds to receptors in the distal or collecting tubules of the kidney and promotes reabsorbtion of water back into the circulation
Vasopressin mechanism of action
Vasopressin acts on three different receptors, vasopressin receptor V1a (which initiates vasoconstriction, liver gluconeogenesis, platelet aggregation and release of factor VIII), vasopressin receptor V1b (which mediates corticotrophin secretion from the pituitary) and vasopressin receptor V2 which controls free water reabsorption in the renal medullar. The binding of vasopressin to the V2 receptor activates adenylate cyclase which causes the release of aquaporin 2 channels into the cells lining the renal medullar duct. This allows water to be reabsorbed down an osmotic gradient so the urine is more concentrated.
Dosage forms of Vasopressin
|Injection||intramuscular; subcutaneous||20 [USP’U]/mL|
|Liquid||intramuscular; subcutaneous||10 unit|
|Liquid||intramuscular; subcutaneous||20 unit|
Humans and other mammals
Indication of Vasopressin
For the treatment of enuresis, polyuria, diabetes insipidus, polydipsia and oesophageal varices with bleeding
Toxicity of Vasopressin
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