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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Venlafaxine

Effexor Xr 37.5 mg Extended-Release Capsule

$1.02

capsule

* price without discount in nearest pharmacy. Price may vary.

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Venlafaxine volume of distribution

* 7.5 3.7 L/kg (venlafaxine) * 5.7 1.8 L/kg (O-desmethylvenlafaxine(active metabolite))

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What is Venlafaxine

Venlafaxine (Effexor) is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class first introduced by Wyeth in 1993. It is prescribed for the treatment of clinical depression and anxiety disorders. Due to the pronounced side effects and suspicions that venlafaxine may significantly increase the risk of suicide it is not recommended as a first line treatment of depression. However, it is often effective for depression not responding to SSRIs. Venlafaxine was the sixth most widely-used antidepressant based on the amount of retail prescriptions in the US (17.1 million) in 2006. (Wikipedia)

Venlafaxine mechanism of action

The exact mechanism of action of venlafaxine is unknown, but appears to be associated with the its potentiation of neurotransmitter activity in the CNS. Venlafaxine and its active metabolite, O-desmethylvenlafaxine (ODV), inhibit the reuptake of both serotonin and norepinephrine with a potency greater for the 5-HT than for the NE reuptake process. Both venlafaxine and the ODV metabolite have weak inhibitory effects on the reuptake of dopamine but, unlike the tricyclics and similar to SSRIs, they are not active at histaminergic, muscarinic, or alpha(1)-adrenergic receptors.

Dosage forms of Venlafaxine

DrugDosageQuantityPrice
Venlafaxine Xr37.5mg100 Capsule$68.00
Venlafaxine Xr75mg84 Capsule$91.00
Venlafaxine Xr150mg28 Capsule$32.00
Effexor XR37.5mg224 Capsule$107.50
Effexor XR75mg84 ER Capsule$64.30
Effexor XR150mg112 ER Capsule$176.20
Desvenlafaxine50mg100 Extended Release Tablet$44.90
Desvenlafaxine100mg100 Extended Release Tablet$67.30
Pristiq50mg28 Extended Release Tablet$80.9
Pristiq100mg84 Extended Release Tablet$188.50
Prescription Generics

false

International Brands

Act Venlafaxine XR

Synonyms

Elafax Venlafaxina

Manufacturers

Actavis Pharma Company

CAS number

93413-69-5

UNII

GRZ5RCB1QG

State

solid

Affected organisms

Humans and other mammals

Indication of Venlafaxine

For the management of major depressive disorder (MDD), generalized anxiety disorder (GAD), social anxiety disorder (social phobia), panic disorder with or without agoraphobia, vasomotor symptoms in women with breast cancer and in postmenopausal women, and neuropathic pain.

Toxicity of Venlafaxine

Most patients overdosing with venlafaxine develop only mild symptoms. However, severe toxicity is reported with the most common symptoms being CNS depression, serotonin toxicity, seizure, or cardiac conduction abnormalities. Venlafaxine’s toxicity appears to be higher than other SSRIs, with a fatal toxic dose closer to that of the tricyclic antidepressants than the SSRIs. Doses of 900 mg or more are likely to cause moderate toxicity. Deaths have been reported following large doses.

RX24 Drugs Disclaimer: before buying a Venlafaxine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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