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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Anoro Ellipta

$120

22mcg

* price without discount in nearest pharmacy. Price may vary.

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Vilanterol volume of distribution

Following IV administration to healthy subjects, the mean volume of distribution at steady state was 661 L.

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What is Vilanterol

Vilanterol is a selective long-acting beta2-adrenergic agonist (LABA) with inherent 24-hour activity for once daily treatment of COPD and asthma. Its pharmacological effect is attributable to stimulation of intracellular adenylyl cyclase which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3′,5′-adenosine monophosphate (cAMP). Increases in cyclic AMP are associated with relaxation of bronchial smooth muscle and inhibition of release of hypersensitivity mediators from mast cells in the lungs. Vilanterol is approved for use in several combination products such as with fluticasone furoate under the tradename Breo Ellipta and in combination with umeclidinium bromide as Anoro Ellipta. Approved by the FDA in 2013, use of Breo Ellipta is indicated for the long-term, once-daily maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and emphysema. It is also indicated for once-daily maintenance treatment of asthma in patients aged 18 or older with reversible obstructive airways disease.

Vilanterol mechanism of action

Vilanterol is a selective long-acting beta2-adrenergic agonist. Its pharmacological effect is attributable to stimulation of intracellular adenylyl cyclase which catalyzes the conversion of adenosine triphosphate (ATP) to cyclic-3′,5′-adenosine monophosphate (cAMP). Increases in cyclic AMP are associated with relaxation of bronchial smooth muscle and inhibition of release of hypersensitivity mediators from mast cells in the lungs.

Dosage forms of Vilanterol

DrugDosageQuantityPrice
Anoro Ellipta22mcg30doses Dry Powder Inhaler$120.00
Anoro Ellipta22mcg90doses Dry Powder Inhaler$346.00
Breo Ellipta22mcg30doses Powder Inhaler$147.00
Breo Ellipta22mcg90doses Powder Inhaler$420.00
Trelegy Ellipta22mcg30 doses Inhalation Powder$133.00
Trelegy Ellipta22mcg90 doses Inhalation Powder$366.00
Prescription Generics

false

International Brands

Anoro Ellipta

Synonyms

4-{(1R)-2-[(6-{2-[(2,6-dichlorobenzyl)oxy]ethoxy}hexyl)amino]-1-hydroxyethyl}-2-(hydroxymethyl)phenol vilanterol

Manufacturers

Glaxosmithkline Inc

CAS number

503068-34-6

UNII

028LZY775B

State

solid

Affected organisms

Indication of Vilanterol

Vilanterol is approved for use in several combination products such as with fluticasone furoate under the tradename Breo Ellipta and in combination with umeclidinium bromide as Anoro Ellipta. Approved by the FDA in 2013, use of Breo Ellipta is indicated for the long-term, once-daily maintenance treatment of airflow obstruction in patients with COPD, including chronic bronchitis and emphysema. It is also indicated for once-daily maintenance treatment of asthma in patients aged 18 or older with reversible obstructive airways disease.

Toxicity of Vilanterol

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