Save up -80% on Vildagliptin

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Vildagliptin

$

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Vildagliptin volume of distribution

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What is Vildagliptin

Vildagliptin, previously identified as LAF237, is a new oral anti-hyperglycemic agent (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Vildagliptin inhibits the inactivation of GLP-1 and GIP by DPP-4, allowing GLP-1 and GIP to potentiate the secretion of insulin in the beta cells and suppress glucaon release by the alpha cells of the islets of Langerhans in the pancreas. It is currently in clinical trials in the U.S. and has been shown to reduce hyperglycemia in type 2 diabetes mellitus. While the drug is still not approved for use in the US, it was approved in Feb 2008 by European Medicines Agency for use within the EU and is listed on the Australian PBS with certain restrictions.

Vildagliptin mechanism of action

Vildagliptin inhibits dipeptidyl peptidase-4 (DPP-4). This in turn inhibits the inactivation of GLP-1 by DPP-4, allowing GLP-1 to potentiate the secretion of insulin in the beta cells. Dipeptidyl peptidase-4’s role in blood glucose regulation is thought to be through degradation of GIP and the degradation of GLP-1.

Dosage forms of Vildagliptin

FormRouteStrength
TabletOral use50 mg
Prescription Generics

International Brands

Synonyms

EQUA Galvus

Manufacturers

CAS number

274901-16-5

UNII

I6B4B2U96P

State

solid

Affected organisms

Humans and other mammals

Indication of Vildagliptin

Used to reduce hyperglycemia in type 2 diabetes mellitus.

Toxicity of Vildagliptin

RX24 Drugs Disclaimer: before buying a Vildagliptin on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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