Save up -80% on Vincristine

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Oncovin

$10.061 vial (2ml) 1mg/ml
price without discount in nearest pharmacy. Price may vary.

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We offer free Vincristine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Vincristine every time. What are you waiting for? Claim your prescription drug card now!

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Vincristine volume of distribution

Within 15 to 30 minutes after injection, over 90% of the drug is distributed from the blood into tissue, where it remains tightly, but not irreversibly, bound.

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About RX24Drugs

2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Vincristine

Vincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin’s disease, acute erythraemia, and acute panmyelosis. vincristine sulfate is often chosen as part of polychemotherapy because of lack of significant bonemarrow suppression (at recommended doses) and of unique clinical toxicity (neuropathy).

Vincristine mechanism of action

The antitumor activity of Vincristine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Like other vinca alkaloids, Vincristine may also interfere with: 1) amino acid, cyclic AMP, and glutathione metabolism, 2) calmodulin-dependent Ca sup2+ /sup-transport ATPase activity, 3) cellular respiration, and 4) nucleic acid and lipid biosynthesis.

Dosage forms of Vincristine

FormRouteStrength
Kit
Liquidintravenous1 mg
Injection, solutionintravenous1 mg/mL

Prescription Generics

false

International Brands

Marqibo

Synonyms

22-Oxovincaleukoblastin 22-Oxovincaleukoblastine

Manufacturers

Talon Therapeutics, Inc.

CAS number

57-22-7

UNII

5J49Q6B70F

State

solid

Affected organisms

Humans and other mammals

Indication of Vincristine

Treatment of acute lymphocytic leukemia (ALL), Hodgkin lymphoma, non-Hodgkin lymphomas, Wilms’ tumor, neuroblastoma, rhabdomyosarcoma. Liposomal vincristine is indicated for the treatment of relapsed Philadelphia chromosome-negative (Ph-) acute lymphoblastic leukemia (ALL).

Toxicity of Vincristine

IVN-RAT LD sub50 /sub 1300 mg/kg; IPR-MUS LD sub50 /sub 5.2 mg/kg. Marqibo must only be administered IV because it is fatal if administered by other routes. Marqibo also has different dosing than vincristine sulphate injection, so attention is needed to prevent overdoses. The most clinically significant adverse effect of vincristine is neurotoxicity.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Vincristine on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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