Save up -80% on Vinorelbine

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RX BIN: 015558
RX PCN: HT
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Vinorelbine

Vinorelbine 50 mg/5 ml vial

$27.6

ml

* price without discount in nearest pharmacy. Price may vary.

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Vinorelbine volume of distribution

* 25.4 to 40.1 L/kg

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What is Vinorelbine

Vinorelbine (Navelbine reg;) is an anti-mitotic chemotherapy drug that is given as a treatment for some types of cancer, including breast cancer and non-small cell lung cancer. (Wikipedia)

Vinorelbine mechanism of action

The antitumor activity of vinorelbine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Vinorelbine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Like other vinca alkaloids, vinorelbine may also interfere with: 1) amino acid, cyclic AMP, and glutathione metabolism, 2) calmodulin-dependent Ca sup 2+ /sup -transport ATPase activity, 3) cellular respiration, and 4) nucleic acid and lipid biosynthesis.

Dosage forms of Vinorelbine

FormRouteStrength
Injectionintravenous10 mg/mL
Injection, solution, concentrateintravenous10 mg/mL
Injection, solution, concentrateintravenous50 mg/5mL
Prescription Generics

false

International Brands

Aj-vinorelbine

Synonyms

5′-Noranhydrovinblastine Nor-5′-anhydrovinblastine

Manufacturers

Agila Jamp Canada Inc

CAS number

71486-22-1

UNII

Q6C979R91Y

State

solid

Affected organisms

Humans and other mammals

Indication of Vinorelbine

For the treatment of non-small-cell lung carcinoma.

Toxicity of Vinorelbine

RX24 Drugs Disclaimer: before buying a Vinorelbine on prescription, consult your healthcare provider. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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