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RX BIN: 015558
Group ID: DDN6600
Card Holder ID: DDN6600

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2018 Price of Vinorelbine

Vinorelbine 50 mg/5 ml vial



* price without discount in nearest pharmacy. Price may vary.

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Vinorelbine volume of distribution

* 25.4 to 40.1 L/kg

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What is Vinorelbine

Vinorelbine (Navelbine reg;) is an anti-mitotic chemotherapy drug that is given as a treatment for some types of cancer, including breast cancer and non-small cell lung cancer. (Wikipedia)

Vinorelbine mechanism of action

The antitumor activity of vinorelbine is thought to be due primarily to inhibition of mitosis at metaphase through its interaction with tubulin. Vinorelbine binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule and mitotic arrest or cell death. Like other vinca alkaloids, vinorelbine may also interfere with: 1) amino acid, cyclic AMP, and glutathione metabolism, 2) calmodulin-dependent Ca sup 2+ /sup -transport ATPase activity, 3) cellular respiration, and 4) nucleic acid and lipid biosynthesis.

Dosage forms of Vinorelbine

Form Route Strength
Injection intravenous 10 mg/mL
Injection, solution, concentrate intravenous 10 mg/mL
Injection, solution, concentrate intravenous 50 mg/5mL
Prescription Generics


International Brands



5′-Noranhydrovinblastine Nor-5′-anhydrovinblastine


Agila Jamp Canada Inc

CAS number






Affected organisms

Humans and other mammals

Indication of Vinorelbine

For the treatment of non-small-cell lung carcinoma.

Toxicity of Vinorelbine

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