Save up -80% on Voriconazole

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Vfend

$1,840.3560 tablets/50mg
price without discount in nearest pharmacy. Price may vary.

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We offer free Vfend coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Voriconazole every time. What are you waiting for? Claim your prescription drug card now!

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Voriconazole volume of distribution

The volume of distribution of voriconazole is 2-4.6 L/kg, suggesting extensive distribution into extracellular and intracellular compartments. Voriconazole was measured in tissue samples of brain, liver, kidney, heart, lung as well as cerebrospinal fluid.

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2018 Statistics

discount card

Discount Cards 16,000+

benefit

Clients Benefit 29%

savings

Total savings $4,735,080

What is Voriconazole

Voriconazole (Vfend, Pfizer) is a triazole antifungal medication used to treat serious fungal infections. It is used to treat invasive fungal infections that are generally seen in patients who are immunocompromised. These include invasive candidiasis, invasive aspergillosis, and emerging fungal infections.

Voriconazole mechanism of action

Voriconazole binds and inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-alpha sterol demethylase. The inhibition of 14-alpha sterol demethylase results in a depletion of ergosterol in fungal cell membrane.

Dosage forms of Voriconazole

DrugDosageQuantityPrice
Voriconazole50mg10 Tablet$89.00
Voriconazole200mg28 Tablet$789.00

Prescription Generics

false

International Brands

Ach-voriconazole

Synonyms

(AlphaR,betas)-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol (R-(R*,s*))-alpha-(2,4-difluorophenyl)-5-fluoro-beta-methyl-alpha-(1H-1,2,4-triazol-1-ylmethyl)-4-pyrimidineethanol

Manufacturers

Accord Healthcare Inc

CAS number

137234-62-9

UNII

JFU09I87TR

State

solid

Affected organisms

Yeast and other fungi

Indication of Voriconazole

For the treatment of esophageal candidiasis, invasive pulmonary aspergillosis, and serious fungal infections caused by iScedosporium apiospermum /i and iFusarium /i spp.

Toxicity of Voriconazole

The minimum lethal oral dose in mice and rats was 300 mg/kg (equivalent to 4 and 7 times the recommended maintenance dose (RMD), based on body surface area). At this dose, clinical signs observed in both mice and rats included salivation, mydriasis, titubation (loss of balance while moving), depressed behavior, prostration, partially closed eyes, and dyspnea. Other signs in mice were convulsions, corneal opacification and swollen abdomen.

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