Save up -80% on Vortioxetine

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Trintellix

$356.6930 tablets/20 mg
price without discount in nearest pharmacy. Price may vary.

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We offer free Trintellix coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Vortioxetine every time. What are you waiting for? Claim your prescription drug card now!

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Vortioxetine volume of distribution

Vortioxetine has a favorable pharmacokinetic profile with dose-proportional and linear exposure, moderate oral bioavailability (75%; independent of food), extensive tissue distribution (steady-state volume of distribution of approximately 2600 L), and a long elimination half-life (66 h).

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2018 Statistics

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Discount Cards 16,000+

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Clients Benefit 29%

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Total savings $4,735,080

What is Vortioxetine

Vortioxetine is an atypical antipsychotic and antidepressant indicated for the treatment of major depressive disorder (MDD). It is classified as a serotonin modulator and simulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and inhibits the reuptake of serotonin. More specifically, vortioxetine acts via the following biological mechanisms: as a serotonin reuptake inhibitor (SRI) through inhibition of the serotonin transporter, as a partial agonist of the 5-HT1B receptor, an agonist of 5-HT1A, and an antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors. SMSs were developed because there are many different subtypes of serotonin receptors, however, not all of these receptors appear to be involved in the antidepressant effects of SRIs. Some serotonin receptors seem to play a relatively neutral or insignificant role in the regulation of mood, but others, such as 5-HT1A autoreceptors and 5-HT7 receptors, appear to play an oppositional role in the efficacy of SRIs in treating depression.

Vortioxetine mechanism of action

Vortioxetine is classified as a serotonin modulator and simulator (SMS) as it has a multimodal mechanism of action towards the serotonin neurotransmitter system whereby it simultaneously modulates one or more serotonin receptors and inhibits the reuptake of serotonin. More specifically, vortioxetine acts via the following biological mechanisms: as a serotonin reuptake inhibitor (SRI) through inhibition of the serotonin transporter, while also acting as a partial agonist of the 5-HT1B receptor, an agonist of 5-HT1A, and antagonist of the 5-HT3, 5-HT1D, and 5-HT7 receptors.

Dosage forms of Vortioxetine

DrugDosageQuantityPrice
Trintellix5mg28 Tablet$167.00
Trintellix5mg84 Tablet$475.00
Trintellix10mg28 Tablet$170.00
Trintellix10mg84 Tablet$428.00
Trintellix20mg56 Tablet$295.00
Trintellix20mg84 Tablet$428.00

Prescription Generics

false

International Brands

Brintellix

Synonyms

4-{2-[(2,4-dimethylphenyl)sulfanyl]phenyl}piperazin-1-ium vortioxetine cation

Manufacturers

Avera Mc Kennan Hospital

CAS number

508233-74-7

UNII

3O2K1S3WQV

State

solid

Affected organisms

Indication of Vortioxetine

Vortioxetine is indicated for the treatment of major depressive disorder (MDD).

Toxicity of Vortioxetine

The most commonly reported adverse effects during clinical trials were nausea, diarrhea, and dry mouth. The FDA label includes a blackbox warning for the following risks and complications: serotonin syndrome, especially when combined with other serotonergic agents; increased risk of abnormal bleeding, especially when combined with NSAIDs, aspirin, or other drugs that affect coagulation; activation of mania/hypomania; hyponatremia; and suicidal thoughts and behaviour in children, adolescents, and young adults.

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Vortioxetine on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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What is a Trintellix?

Trintellix is ​​an antidepressant that affects chemicals in the brain that may be unbalanced. Trintellix is ​​used to treat major depressive disorders in adults. Do not use Trintellix if you have used a MAO inhibitor in the past 14 days, such as isocarboxazid, methylene blue injection, fenelzine, rasagiline, selegiline, or tranylcypromine. After you stop taking Trintellix, you must wait at least 21 days before you start taking a MAO inhibitor.

Some young people have thoughts about suicide when they first take an antidepressant. Watch for changes in mood or symptoms. Report any new or worsening symptoms to your doctor, such as: changes in mood or behavior, anxiety, panic attacks, sleep problems, or if you feel impulsive, irritable, agitated, hostile, aggressive, anxious, hyperactive (mentally or physically), More depressed or thinking about suicide or hurting yourself.

Do not give Trintellix to anyone under 18 without consulting a doctor. This medicine is not approved for use in children.