Save up -80% on Zalcitabine

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Zalcitabine

Hivid 0.375 mg tablet

price without discount in nearest pharmacy. Price may vary.

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We offer free Zalcitabine coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your discount card in most local pharmacies to get a discount on Zalcitabine every time. What are you waiting for? Claim your prescription drug card now!

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Zalcitabine volume of distribution

* 0.304 to 0.734 L/kg

RX Prescription
Ask Your therapeut before taking any drugs.

About RX24Drugs

2018 Statistics

discount card

Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Zalcitabine

A dideoxynucleoside compound in which the 3′-hydroxyl group on the sugar moiety has been replaced by a hydrogen. This modification prevents the formation of 5′ to 3′ phosphodiester linkages, which are needed for the elongation of DNA chains, thus resulting in the termination of viral DNA growth. The compound is a potent inhibitor of HIV replication at low concentrations, acting as a chain-terminator of viral DNA by binding to reverse transcriptase. Its principal toxic side effect is axonal degeneration resulting in peripheral neuropathy.

Zalcitabine mechanism of action

Zalcitabine is a nucleoside reverse transcriptase inhibitor (NRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Within cells, zalcitabine is converted to its active metabolite, dideoxycytidine 5′-triphosphate (ddCTP), by the sequential action of cellular enzymes. ddCTP interferes with viral RNA-directed DNA polymerase (reverse transcriptase) by competing for utilization of the natural substrate deoxycytidine 5′-triphosphate (dCTP), as well as incorpating into viral DNA. Due to it’s lack of a 3′-OH group, the formation of a 5′ to 3′ phosphodiester linkage that is necessary for DNA chain elongation is inhibited, thus leading to the termination of viral DNA growth.

Dosage forms of Zalcitabine

Tabletoral.375 mg
Tabletoral.75 mg

Prescription Generics


International Brands

Hivid Tab 0.375mg


2′,3′-Dideoxycytidine 4-amino-1-((2R,5S)-5-(Hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one


Hoffmann La Roche Limited

CAS number






Affected organisms

Human Immunodeficiency Virus

Indication of Zalcitabine

For the treatment of Human immunovirus (HIV) infections in conjunction with other antivirals.

Toxicity of Zalcitabine

Acute overdose: Inadvertent pediatric overdoses have occurred with doses up to 1.5 mg/kg zalcitabine. Chronic overdose: in an initial dose-finding study in which zalcitabine was administered at doses 25 times (0.25 mg/kg every 8 hours) the currently recommended dose, one patient discontinued zalcitabine after 1 weeks of treatment subsequent to the development of a rash and fever.

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