Save up -80% on Zidovudine

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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Retrovir

$21.5860 tablets/300mg
Price with discount in nearest pharmacy. Price may vary.

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We offer free Retrovir coupons and discounts that may help you save up to 80% off the retail price in your local pharmacy. Just print your coupon! It’s ready to use and never expire. Present your manufacturer copay card in most local pharmacies to get a discount on Zidovudine every time. What are you waiting for? Claim your prescription drug card now!

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Zidovudine volume of distribution

Zidovudine AUC was similar when a single dose of zidovudine was administered with food. Protein Binding 34-38% Volume of Distribution 1.6 L/kg CSF:Plasma ratio 0.5 Semen:Plasma ratio 5.9 (0.95-13.5) Renal Clearance Greatly exceeds creatinine clearance, indicating that significant tubular secretion takes place.

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2018 Statistics

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Discount Cards 16,000+


Clients Benefit 29%


Total savings $4,735,080

What is Zidovudine

A dideoxynucleoside compound in which the 3 #39;-hydroxy group on the sugar moiety has been replaced by an azido group. This modification prevents the formation of phosphodiester linkages which are needed for the completion of nucleic acid chains. The compound is a potent inhibitor of HIV replication, acting as a chain-terminator of viral DNA during reverse transcription. It improves immunologic function, partially reverses the HIV-induced neurological dysfunction, and improves certain other clinical abnormalities associated with AIDS. Its principal toxic effect is dose-dependent suppression of bone marrow, resulting in anemia and leukopenia.

Zidovudine mechanism of action

Zidovudine, a structural analog of thymidine, is a prodrug that must be phosphorylated to its active 5.-triphosphate metabolite, zidovudine triphosphate (ZDV-TP). It inhibits the activity of HIV-1 reverse transcriptase (RT) via DNA chain termination after incorporation of the nucleotide analogue. It competes with the natural substrate dGTP and incorporates itself into viral DNA. It is also a weak inhibitor of cellular DNA polymerase . and ..

Dosage forms of Zidovudine

Retrovir100mg100 Capsule$295.00
Retrovir Syrup10mg/mL240mL Oral suspension$85.00
Zidovudine100mg100 Capsule$95.00
Zidovudine300mg60 Capsule$85.00
Lamivudine/Zidovudine150/300mg60 Tablet$68.10
Lamivudine/Zidovudine150/300mg120 Tablet$135.00
Combivir150/300mg60 Tablet$670.00
Trizivir300/150/300mg60 Tablet$1,550.00

Prescription Generics


International Brands

Abacavir Sulfate, Lamivudine and Zidovudine


Azidothymidine AZT



CAS number






Affected organisms

Human Immunodeficiency Virus

Indication of Zidovudine

Used in combination with other antiretroviral agents for the treatment of human immunovirus (HIV) infections.

Toxicity of Zidovudine

Symptoms of overdose include fatigue, headache, nausea, and vomiting. LD sub50 /sub is 3084 mg/kg (orally in mice).

RX24 Drugs Disclaimer: consult your healthcare provider before buying a Zidovudine on prescription or using an RX manufacturer savings coupon. Content on this page is provided for informational purposes only. Any use of this information is at your own risk.

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