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RX BIN: 015558RX PCN: HTGroup ID: DDN6600Card Holder ID: DDN6600
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2019 Price of Ambien

$8.0630 tablets/10 mg
price without discount in nearest pharmacy. Price may vary.

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Zolpidem volume of distribution

The volume of distribution (Vol D) of zolpidem in healthy volunteers was 0.54 L per kg (L/kg) following an 8 mg intravenous dose.

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2018 Statistics

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Discount Cards 16,000+

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Clients Benefit 29%

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Total savings $4,735,080

What is Zolpidem

Zolpidem is a prescription short-acting nonbenzodiazepine hypnotic that potentiates gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter, by binding to benzodiazepine receptors which are located on the gamma-aminobutyric acid receptors. Zolpidem is used for the short-term treatment of insomnia. It works quickly (usually within 15 minutes) and has a short half-life (2-3 hours). It is classified as an imidazopyridine. As an anticonvulsant and muscle relaxant, the beneficial effects start to emerge at 10 and 20 times the dose required for sedation, respectively. For that reason, it has never been approved for either muscle relaxation or seizure prevention. Recently, zolpidem has been cited in various medical reports mainly in the United Kingdom as waking persistent vegetative state (PVS) patients, and dramatically improving the conditions of people with brain injuries. (Wikipedia)

Zolpidem mechanism of action

Zolpidem modulates the alpha-subunit, known as the benzodiazepine receptor, within the GABA subA /sub receptor chloride channel macromolecular complex. Unlike the benzodiazepines, which non-selectively interact with all three alpha-receptor subtypes, Zolpidem preferentially binds to the alpha-1 receptor.

Dosage forms of Zolpidem

FormRouteStrength
Tabletoral6.25 mg/1
Tablet, coatedoral12.5 mg/1
Tablet, coatedoral6.25 mg/1

Prescription Generics

false

International Brands

Ambien

Synonyms

N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamide Zolpidem

Manufacturers

A S Medication Solutions Llc

CAS number

82626-48-0

UNII

7K383OQI23

State

solid

Affected organisms

Humans and other mammals

Indication of Zolpidem

For the short-term treatment of insomnia.

Toxicity of Zolpidem

Oral (male rat) LD sub50 /sub = 695 mg/kg. Symptoms of overdose include impairment of consciousness ranging from somnolence to light coma.

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