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Price of Zopiclone
Imovane 5 mg Tablet
* price without discount in nearest pharmacy. Price may vary.
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Zopiclone volume of distribution
What is Zopiclone
Zopiclone is a novel hypnotic agent used in the treatment of insomnia. Its mechanism of action is based on modulating benzodiazepine receptors. In addition to zopiclone’s benzodiazepine pharmacological properties it also has some barbiturate like properties.
Zopiclone mechanism of action
Zopiclone exerts its action by binding on the benzodiazepine receptor complex and modulation of the GABA subB /subZ receptor chloride channel macromolecular complex. Both zopiclone and benzodiazepines act indiscriminately at the benzodiazepine binding site on .1, .2, .3 and .5 GABAA containing receptors as full agonists causing an enhancement of the inhibitory actions of GABA to produce the therapeutic (hypnotic and anxiolytic) and adverse effects of zopiclone.
Dosage forms of Zopiclone
Actavis Pharma Company
Humans and other mammals
Indication of Zopiclone
For the short-term treatment of insomnia.
Toxicity of Zopiclone
Rare individual instances of fatal outcomes following overdose with racemic zopiclone have been reported in European postmarketing reports, most often associated with overdose with other CNS-depressant agent. Signs and symptoms of overdose effects of CNS depressants can be expected to present as exaggerations of the pharmacological effects noted in preclinical testing.
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