Anti-inflammatory drugs are an extensive group of pharmacological agents that are used in medical practice. Their prevalence is due to high efficiency in eliminating pain syndrome, fever and inflammation foci with minimal side effects for the body. Analgesic and anti-inflammatory properties are proven in numerous medical trials.
The mechanisms of action of nonsteroidal anti-inflammatory drugs are similar and boil down to inhibition of cyclooxygenase activity, an enzyme that regulates the production of arachidonic acid. Also, the effect is due to the slowing down of the oxidation of fats, the stabilization of membranes and the decrease in the synthesis of ATP. The processes of neutrophil aggregation and formation of rheumatoid factors also slow down.
Steroid drugs are synthesized based on glucocorticoids – hormones that are secreted by the adrenal glands. Non-steroidal drugs have similar efficacy, but they do not have significant side effects-they do not cause hypertension, diabetes, and addiction. Therefore, each time you do not need to increase the dosage or completely change the drug.