Antibacterial drugs – the so-called whole cluster of drugs that have the property to suppress the growth and development of living cells of harmful microorganisms or cause their death. Therefore, they are used in the treatment of inflammatory processes that were caused by bacterial microflora. Such drugs have selective toxicity, in which human cells are not damaged.
Antibacterial action is the ability of drugs to inhibit reproduction and cause the death of bacteria. It is realized during the violation of the synthesis of the bacterial wall, protein, as well as the synthesis of the DNA of the microorganism (by DNA damage, DNA gyrase suppression, inhibition of RNA polymerase activity, inhibition of folic acid production). By the type of effect on bacterial cells, antibacterial action can be bactericidal and bacteriostatic.
The bactericidal effect of drugs means the ability to cause the death of microorganisms, damaging cell membranes. The bacteriostatic action of drugs is based on inhibition of protein synthesis and suppression of microorganism multiplication. Preparations with antibacterial action are used in the treatment of various infectious diseases, as well as the prevention of infectious complications.