The microflora of the vagina is relatively constant; the immune and endocrine systems regulate it. Normally, there are sufficiently reliable mechanisms in the vagina to protect against pathogenic pathogens. There are also some factors that can disrupt protective mechanisms, thereby increasing the risk of inflammatory diseases of the vulva and vagina. In particular, hormonal changes during the menstrual cycle, during pregnancy, various age periods are of great importance.
The change may occur due to the biocenosis antibiotic therapy, corticosteroids, cytostatics and other drugs for vaginal douching using an intrauterine contraceptive, tampons, diaphragms, and the frequent use of spermicides, promiscuity. These factors lead to an imbalance of vaginal flora, resulting in growth of opportunistic especially anaerobic flora.
The goal of treatment vulvovaginal infections is primarily in the eradication of pathogens, and in most cases, it must begin empirically, immediately after the establishment of the preliminary diagnosis. Treatment must necessarily be comprehensive. Given that most patients reveal precisely mixed infection, great importance is the combination of one preparation of several active ingredients, which makes it possible to achieve a therapeutic effect.
In treating vulvovaginitis mixed etiology successfully used a combination of drugs, including an anti-fungal agent, an antiseptic and/or antibacterial preparation, characterized by high clinical efficacy.